Correlation between serum 25(OH)D levels with severity of work-related hand eczema among healthcare workers: a cross-sectional study
https://doi.org/10.4081/dr.2023.9861
HTML: 11
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Hand eczema (HE) is a common condition seen in medical facilities, particularly during the COVID-19 pandemic. The effects of vitamin D on skin inflammation are diverse. The purpose of this study is to examine the relationship between vitamin D levels in healthcare workers as determined by serum 25(OH)D and the severity of HE. In Indonesia, between September and October of 2022, a cross-sectional design was employed for this analytical descriptive study. The hand eczema severity index was used to determine the severity of HE. Out of the 44 healthcare workers who had HE, the findings indicated that 29 had mild HE, 11 had moderate HE, and 4 had severe HE. Subjects with mild, moderate, and severe HE had mean serum 25(OH)D levels of 17.85 ng/mL, 16.45 ng/mL, and 17.87 ng/mL, respectively, falling into the vitamin D deficiency category. Serum 25(OH)D levels and the severity of HE did not significantly correlate (r=-0.056; p=0.359). Serum 25(OH)D levels did not significantly differ between subjects with mild, moderate, and severe HE. The degree of HE was not negatively correlated with serum 25(OH)D levels.
Capucci S, Hahn-Pedersen J, Vilsboll A, Kragh N. Impact of atopic dermatitis and chronic hand eczema on quality of life compared with other chronic diseases. Dermatitis 2020;31:178-84.
Quaade AS, Simonsen AB, Halling AS, et al. Prevalence, incidence, and severity of hand eczema in the general population - A systematic review and meta-analysis. Contact Dermatitis 2021;84:361-74.
Yusuf RS, Qurratuaini BPA, Hidajat D. Efek hand hygiene terhadap dermatitis tangan. JKU Unram 2021;10:480-6.
Rundle CW, Presley CL, Militello M, et al. Hand hygiene during COVID-19: Recommendations from the American Contact Dermatitis Society. J Am Acad Dermatol 2020;83:1730-7.
Sawitri, Astindari, Yuindartanto A, et al. Epidemiology of occupational contact dermatitis (OCD) on health workers in COVID-19. J Pak Assoc Dermatol 2023;33:220-34.
Samanta S. Vitamin D and immunomodulation in the skin: a useful affirmative nexus. Explor Immunol 2021.
Amon U, Baier L, Yaguboglu R, et al. Serum 25-hydroxyvitamin D levels in patients with skin diseases including psoriasis, infections, and atopic dermatitis. Dermatoendocrinol 2018;10:e1442159.
Suryadinata RV, Lorensia A, Aprilia AP. Profil vitamin D pada pasien asma dan non-asma dewasa di Surabaya. IJPH 2017;12.
Held E, Skoet R, Johansen JD, Agner T. The hand eczema severity index (HECSI): A scoring system for clinical assessment of hand eczema. A study of inter- and intraobserver reliability. Br J Dermatol 2005;152:302-7.
Park JB, Lee SH, Kim KJ, et al. Clinical features and awareness of hand eczema in Korea. Ann Dermatol 2016;28:335-43.
Safizadeh H, Shamsi-Meymandy S, Nasri L, Shamsi????Meymandy M. Quality of life among patients with hand eczema in Iran. RusOMJ 2013;2:1-4.
Georgieva FG. Hand eczema and its impact on wellbeing and quality of life of patients. J IMAB 2017;23:1490-4.
Madan I, Parsons V, Cookson B, et al. A behavioural change package to prevent hand dermatitis in nurses working in the national health service (the SCIN trial): study protocol for a cluster randomised controlled trial. Trials 2016;17:145.
Celik V, Ozkars MY. An overlooked risk for healthcare workers amid COVID-19: Occupational hand eczema. North Clin Istanb 2020;7:527-33.
Techasatian L, Thaowandee W, Chaiyarit J, et al. Hand hygiene habits and prevalence of hand eczema during the COVID-19 pandemic. J Prim Care Community Health 2021;12:1-5.
Loh EW, Yew YW. Hand hygiene and hand eczema: a systematic review and meta-analysis. Contact Dermatitis 2022.
Nopriyati, Trilisnawati D, Yulia Farida Y, et al. Prevention of irritant contact dermatitis due to hand hygiene in the era of COVID 19 pandemic. BSM 2020;4:29-44.
Desira ADD, Riyanto P, Afriliana L, Adespin DA. Relationship of hand sanitizer usage frequency with the incidence of irritant contact dermatitis during COVID-19 pandemic. JKD 2022;11:109-13.
Kodik MS, Çetin ZD, Unal İ, Altuncı YA. The prevalence and risk factors of hand eczema among emergency healthcare workers during the COVID-19 pandemic. Ege Tip Dergisi 2021;60:155-62.
Alkhalifah A. Risk factors for hand eczema in the general population of Saudi Arabia during the COVID-19 pandemic: An internet-based cross-sectional study. JAAD Int 2022;6:119-24.
Hamnerius N, Svedman C, Bergendorff O, et al. Hand eczema and occupational contact allergies in healthcare workers with a focus on rubber additives. Contact Dermatitis 2018;79:149-56.
Behroozy A, Keegel TG. Wet-work exposure: a main risk factor for occupational hand dermatitis. Saf Health Work 2014;5:175-80.
Loman L, Politiek K, Schuttelaar MLA. Smoking and obesity are associated with chronic hand eczema and severity of hand eczema: Data from the Dutch general population. Contact Dermatitis 2022;87:103-6.
Charan UP, Peter CV, Pulimood SA. Impact of hand eczema severity on quality of life. Indian Dermatol Online J 2013;4:102-5.
Mahajan BB, Kaur S. Impact of hand eczema severity on quality of life: a hospital based cross-sectional study. Dermatol Online 2016;7:1-4.
Varma R, Devi K, Asokan N. A cross-sectional analysis on hand eczema: severity and quality of life. Indian Dermatol Online J 2021;12:952-3.
Sari DK, Sari LM, Laksmi LI, Farhat. The moderate correlation between 25(OH)D serum and saliva in healthy people with low vitamin D intake. Int J Gen Med 2021;14:841-50.
Methkal AM, Kuts LV. The investigation of the dependence between hand eczema severity and some cytokine profile parameters, vitamin D level, and glucocorticoid receptor gene polymorphism. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 2020;5:164-9.
Huang CM, Lara-Corrales I, Pope E. Effects of vitamin D levels and supplementation on atopic dermatitis: A systematic review. Pediatr Dermatol 2018;35:754-60.
Hafsia M, Kacem I, El Maalel O, et al. Relationship between hand eczema severity and occupational stress: a cross sectional study. Dermatol Res Pract 2019;2019:8301896.
Copyright (c) 2023 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Downloads
Citations
