Molluscum contagiosum eruption during therapy with methotrexate and abatacept: a clinical and dermoscopic case study


Submitted: 9 May 2021
Accepted: 4 December 2021
Published: 21 March 2022
Abstract Views: 719
PDF: 379
HTML: 388
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

The use of multiple drugs acting as modulators of the immune system are common among patients with severe autoimmune diseases. In these clinical scenarios, great attention should be placed on diagnosing infective cutaneous disorders that can underly iatrogenic immunosuppression. Here within, we report a rare case of molluscum contagiosum eruption on the face and the scalp during an immunomodulating treatment for rheumatoid arthritis, with clinical and dermatoscopic characterization.


Edwards S, Boffa MJ, Janier M, et al. European guideline on the management of genital molluscum contagiosum. J Eur Acad Dermatol Venereol 2021;35:17-26. DOI: https://doi.org/10.1111/jdv.16856

Chen X, Anstey AV, Bugert JJ. Molluscum contagiosum virus infection. Lancet Infect Dis 2013;13:877-88. DOI: https://doi.org/10.1016/S1473-3099(13)70109-9

Beutler BD, Cohen PR. Molluscum contagiosum of the eyelid: case report in a man receiving methotrexate and literature review of molluscum contagiosum in patients who are immunosuppressed secondary to methotrexate or HIV infection. Dermatol Online J 2016;22:13030. DOI: https://doi.org/10.5070/D3223030363

Ianhez M, Cestari Sda C, Enokihara MY, Seize MB. Dermoscopic patterns of molluscum contagiosum: a study of 211 lesions confirmed by histopathology. An Bras Dermatol 2011;86:74-9. DOI: https://doi.org/10.1590/S0365-05962011000100009

Annam V, Inamadar AC, Palit A, Yelikar BR. Co-infection of molluscum contagiosum virus and cryptococcosis in the same skin lesion in a HIV-infected patient. J Cutan Pathol 2008;35:29-31. DOI: https://doi.org/10.1111/j.1600-0560.2008.00980.x

Madan V, August PJ. Facial molluscum contagiosum in a patient with rheumatoid arthritis taking methotrexate. Clin Exp Dermatol 2008;33:347. DOI: https://doi.org/10.1111/j.1365-2230.2007.02684.x

Nakamura-Wakatsuki T, Kato Y, Miura T, Yamamoto T. Eruptive molluscum contagiosum in a patient with rheumatoid arthritis and lung cancer. Rheumatol Int 2011;31:1117-8. DOI: https://doi.org/10.1007/s00296-010-1696-7

Bansal S, Relhan V, Roy E, et al. Disseminated molluscum contagiosum in a patient on methotrexate therapy for psoriasis. Indian J Dermatol Venereol Leprol 2014;80:179-80. DOI: https://doi.org/10.4103/0378-6323.129418

Wetzel M, Tidwell WJ, Callen JP. Disseminated molluscum contagiosum associated with immunomodulatory therapy. JAAD Case Rep 2020;6:708-9. DOI: https://doi.org/10.1016/j.jdcr.2020.06.018

Taviti, F., Calcinai, A., & Scarfì, F. . (2022). <i>Molluscum contagiosum</i> eruption during therapy with methotrexate and abatacept: a clinical and dermoscopic case study. Dermatology Reports, 14(3). https://doi.org/10.4081/dr.2022.9259

Downloads

Download data is not yet available.

Citations