Unusual presentation of angiolymphoid hyperplasia with eosinophilia treated with intralesional and topic corticosteroid combination therapy
Submitted: 30 December 2020
Accepted: 3 March 2021
Published: 15 September 2021
Accepted: 3 March 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon angioproliferative benign disorder. A 24- year-old Caucasian female patient presented with multiple itchy reddish pearly nodule.
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2. Fontana SC, Borgstadt A, Fraga GR et al. Angiolymphoid Hyperplasia With Eosinophilia Within a Vascular Malformation: Case Report and Review of the Literature. Ann Otol Rhinol Laryngol. 2016 Sep;125(9):775-8.
3.Arnold M, Geilen CC, Coupland SE et al. Unilateral angiolymphoid hyperplasia with eosino-philia involving the left arm and hand. J Cutan Pathol. 1999 Oct;26(9):436-40.
4. Dewan P, Francis ND, Lear JT, Bunker CB. Angiolymphoid hyperplasia with eosinophilia af-fecting the penis. Br J Dermatol. 2008 Sep;159(3):755-7.
5. Nonose R, Priolli DG, Cardinalli IA et al. Epithelioid hemangioma of the colon: a case re-port. Sao Paulo Med J. 2008 Sep;126(5):294-6.
6. Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol. 1985 May;12(5 Pt 1):781-96.
7. Guo R, Gavino AC. Angiolymphoid hyperplasia with eosinophilia. Arch Pathol Lab Med. 2015 May;139(5):683-6.
8. Parmar NV, Sandu J, Kanwar AJ, Saikia UN. Angiolymphoid hyperplasia with eosinophilia of the infra-axillary region: report of a case. Dermatol Online J. 2014 Mar 17;20(3)
9. Kempf W, Haeffner AC, Zepter K, Sander CA, et al. Angiolymphoid hyperplasia with eosin-ophilia: evidence for a T-cell lymphoproliferative origin. Hum Pathol. 2002 Oct;33(10):1023-9.
10. Abrahamson TG, Davis DA. Angiolymphoid hyperplasia with eosinophilia responsive to pulsed dye laser. J Am Acad Dermatol. 2003 Aug;49(2 Suppl Case Reports):S195-6.
11.Kaur T, Sandhu K, Gupta S et al. Treatment of angiolymphoid hyperplasia with eosinophilia with the carbon dioxide laser. J Dermatolog Treat. 2004 Sep;15(5):328-30.
12. Woźniacka A, Omulecki A, Torzecka JD. Cryotherapy in the treatment of angiolymphoid hyperplasia with eosinophilia. Med Sci Monit. 2003 Jan;9(1):CS1-4.
13. Shenefelt PD, Rinker M, Caradonna S. A case of angiolymphoid hyperplasia with eosino-philia treated with intralesional interferon alfa-2a. Arch Dermatol. 2000 Jul;136(7):837-9.
14. Carlesimo M, Mari E, Tammaro A et al. Angiolymphoid hyperplasia with eosinophilia trea-ted with isotretinoin. Eur J Dermatol. 2007 Nov-Dec;17(6):554-5.
15. Mashiko M, Yokota K, Yamanaka Y, Furuya K. A case of angiolymphoid hyperplasia with eosinophilia successfully treated with tacrolimus ointment. Br J Dermatol. 2006 Apr;154(4):803-4.
16. Braun-Falco M, Fischer S, Plötz SG, Ring J. Angiolymphoid hyperplasia with eosinophilia treated with anti-interleukin-5 antibody (mepolizumab). Br J Dermatol. 2004 Nov;151(5):1103-4.
2. Fontana SC, Borgstadt A, Fraga GR et al. Angiolymphoid Hyperplasia With Eosinophilia Within a Vascular Malformation: Case Report and Review of the Literature. Ann Otol Rhinol Laryngol. 2016 Sep;125(9):775-8.
3.Arnold M, Geilen CC, Coupland SE et al. Unilateral angiolymphoid hyperplasia with eosino-philia involving the left arm and hand. J Cutan Pathol. 1999 Oct;26(9):436-40.
4. Dewan P, Francis ND, Lear JT, Bunker CB. Angiolymphoid hyperplasia with eosinophilia af-fecting the penis. Br J Dermatol. 2008 Sep;159(3):755-7.
5. Nonose R, Priolli DG, Cardinalli IA et al. Epithelioid hemangioma of the colon: a case re-port. Sao Paulo Med J. 2008 Sep;126(5):294-6.
6. Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol. 1985 May;12(5 Pt 1):781-96.
7. Guo R, Gavino AC. Angiolymphoid hyperplasia with eosinophilia. Arch Pathol Lab Med. 2015 May;139(5):683-6.
8. Parmar NV, Sandu J, Kanwar AJ, Saikia UN. Angiolymphoid hyperplasia with eosinophilia of the infra-axillary region: report of a case. Dermatol Online J. 2014 Mar 17;20(3)
9. Kempf W, Haeffner AC, Zepter K, Sander CA, et al. Angiolymphoid hyperplasia with eosin-ophilia: evidence for a T-cell lymphoproliferative origin. Hum Pathol. 2002 Oct;33(10):1023-9.
10. Abrahamson TG, Davis DA. Angiolymphoid hyperplasia with eosinophilia responsive to pulsed dye laser. J Am Acad Dermatol. 2003 Aug;49(2 Suppl Case Reports):S195-6.
11.Kaur T, Sandhu K, Gupta S et al. Treatment of angiolymphoid hyperplasia with eosinophilia with the carbon dioxide laser. J Dermatolog Treat. 2004 Sep;15(5):328-30.
12. Woźniacka A, Omulecki A, Torzecka JD. Cryotherapy in the treatment of angiolymphoid hyperplasia with eosinophilia. Med Sci Monit. 2003 Jan;9(1):CS1-4.
13. Shenefelt PD, Rinker M, Caradonna S. A case of angiolymphoid hyperplasia with eosino-philia treated with intralesional interferon alfa-2a. Arch Dermatol. 2000 Jul;136(7):837-9.
14. Carlesimo M, Mari E, Tammaro A et al. Angiolymphoid hyperplasia with eosinophilia trea-ted with isotretinoin. Eur J Dermatol. 2007 Nov-Dec;17(6):554-5.
15. Mashiko M, Yokota K, Yamanaka Y, Furuya K. A case of angiolymphoid hyperplasia with eosinophilia successfully treated with tacrolimus ointment. Br J Dermatol. 2006 Apr;154(4):803-4.
16. Braun-Falco M, Fischer S, Plötz SG, Ring J. Angiolymphoid hyperplasia with eosinophilia treated with anti-interleukin-5 antibody (mepolizumab). Br J Dermatol. 2004 Nov;151(5):1103-4.
Granieri, G., Oranges, T., Panduri, S., Loggini, B., Janowska, A., Dini, V. ., & Romanelli, M. (2021). Unusual presentation of angiolymphoid hyperplasia with eosinophilia treated with intralesional and topic corticosteroid combination therapy. Dermatology Reports, 13(2). https://doi.org/10.4081/dr.2021.9063
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