Subclinical onychomycosis in patients with type II diabetes


Submitted: 5 July 2015
Accepted: 7 July 2015
Published: 17 December 2015
Abstract Views: 1688
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Authors

  • Amira Elbendary Department of Dermatology, Kasr Al Ainy Faculty of Medicine, Cairo University, Egypt; Ackerman Academy of Dermatopathology, New York, NY, United States.
  • Amira El Tawdy Department of Dermatology, Kasr Al Ainy Faculty of Medicine, Cairo University, Egypt.
  • Naglaa Zaki Department of Dermatology, Kasr Al Ainy Faculty of Medicine, Cairo University, Egypt.
  • Mostafa Alfishawy Department of Internal Medicine, Kasr Al Ainy Faculty of Medicine, Cairo University, Egypt; Department of Medicine, Queens Hospital Center/Ichan school of Medicine at Mount Sinai, New York, NY, United States.
  • Amr Rateb Department of Dermatology, Kasr Al Ainy Faculty of Medicine, Cairo University, Egypt.
Fungal organisms could be present in the nail without any clinical manifestations. As onychomycosis in diabetics has more serious complications, early detection of such infection could be helpful to prevent them. We aim in this study to assess the possibility of detecting subclinical onychomycosis in type II diabetic patients and addressing possible associated neuropathy. A cross sectional, observational study included patients with type II diabetes with normal big toe nail. All were subjected to nail clipping of the big toe nail, followed by staining with Hematoxylin and Eosin and Periodic-Acid-Schiff (PAS) stains and examined microscopically. A total of 106 patients were included, fungal infection was identified in eight specimens, all were uncontrolled diabetes, and six had neuropathy. Using the nail clipping and microscopic examination with PAS stain to detect such subclinical infection could be an applicable screening test for diabetic patients, for early detection and management of onychomycosis.

Supporting Agencies


Elbendary, A., El Tawdy, A., Zaki, N., Alfishawy, M., & Rateb, A. (2015). Subclinical onychomycosis in patients with type II diabetes. Dermatology Reports, 7(3). https://doi.org/10.4081/dr.2015.6099

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