Orofacial granulomatosis in children can be the initial manifestation of systemic disease: a presentation of two cases

Anne Birgitte Simonsen; Mette Deleuran

doi:10.4081/dr.2014.5039

Orofacial granulomatosis in children can be the initial manifestation of systemic disease: a presentation of two cases

https://doi.org/10.4081/dr.2014.5039

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Vol. 6 No. 1 (2014)

Submitted: 20 August 2013
Accepted: 20 December 2013

Published: 12 May 2014

orofacial granulomatosis, children, Chron's disease

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Authors

Anne Birgitte Simonsen
anbsim@rm.dk
Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Mette Deleuran Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.

Orofacial granulomatosis is a chronic granulomatous condition characterized by relapsing and remitting lip swelling and oral involvement that may include deep ulcers, tags and cobblestone formation. It occurs as an independent entity but also in conjunction with systemic diseases such as tuberculosis, sarcoidosis and Crohn’s disease. The clinical presentation is not indicative of concomitant systemic disease. To highlight the importance of thorough examination to rule out systemic disease, we present two childhood cases of orofacial granulomatosis, one of which was associated to Crohn’s disease.

Supporting Agencies

Simonsen, A. B., & Deleuran, M. (2014). Orofacial granulomatosis in children can be the initial manifestation of systemic disease: a presentation of two cases. Dermatology Reports, 6(1). https://doi.org/10.4081/dr.2014.5039