Vol. 1 No. 1 (2020)

Published: 14-02-2020

Editorials

Biomedical Science and Engineering: a new multidisciplinary journal dealing with modern regenerative medicine strategies

Valeria Chiono

https://doi.org/10.4081/bse.4

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Published: 30 May 2016

982

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The Italian Centro 3R: Mission and early achievements presented during the Second Annual Meeting

Arti Ahluwalia

https://doi.org/10.4081/bse.79

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Published: 11 February 2020

457

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Original Articles

Nerve guidance conduits based on bi-layer chitosan membranes for peripheral nerve regeneration

Francesca Ruini, Chiara Tonda-Turo, Stefania Raimondo, Pierluigi Tos, Pierfrancesco Pugliese, Stefano Geuna, Gianluca Ciardelli

https://doi.org/10.4081/bse.12

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Published: 30 May 2016

1205

PDF: 477
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Injectable thermosensitive gels for the localized and controlled delivery of biomolecules in tissue engineering/regenerative medicine

Monica Boffito, Arianna Grivet Brancot, Ornella Lima, Simona Bronco, Susanna Sartori, Gianluca Ciardelli

https://doi.org/10.4081/bse.67

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Published: 9 July 2019

895

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Investigating the microenvironmental effects of scaffold chemistry and topology in human mesenchymal stromal cell/polymeric hollow microfiber constructs

Claudio Ricci, Luisa Trombi, Ilaria Soriga, Fabio Piredda, Mario Milazzo, Cesare Stefanini, Luca Bruschini, Giuseppe Perale, Gianni Pertici, Serena Danti

https://doi.org/10.4081/bse.10

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Published: 30 May 2016

1026

PDF: 462
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Layer-by-layer coating of stainless steel plates mediated by surface priming treatment to improve antithrombogenic properties

Irene Carmagnola, Tiziana Nardo, Francesca Boccafoschi, Valeria Chiono

https://doi.org/10.4081/bse.22

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Published: 30 May 2016

806

PDF: 394
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Ethical issues in Ph.D. training at the Politecnico di Milano

Andrea Aliverti

https://doi.org/10.4081/bse.80

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Published: 12 February 2020

412

PDF: 253
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Development of an animal-free methodology for mechanical performance assessment of engineered skin substitutes

Alessandra Aldieri, Mara Terzini, Diana Massai, Cristina Bignardi, Alberto Audenino

https://doi.org/10.4081/bse.103

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Published: 12 February 2020

1875

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Real-time cellular impedance monitoring and imaging in a dual-flow bioreactor

Ludovica Cacopardo, Joana Costa, Nicole Guazzelli, Serena Giusti, Sandro Meucci, Alessandro Corti, Giorgio Mattei, Arti Ahluwalia

https://doi.org/10.4081/bse.104

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Published: 12 February 2020

1470

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Teaching and training in substitutive approaches to animal testing: Commitment of the University of Genoa

Anna Maria Bassi

https://doi.org/10.4081/bse.81

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Published: 11 February 2020

470

PDF: 290
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Reconstituted epithelial corneal tissues for evaluation of drug delivery

Susi Burgalassi, Erica Zucchetti, Eleonora Terreni, Daniela Monti, Silvia Tampucci, Patrizia Chetoni

https://doi.org/10.4081/bse.82

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Published: 11 February 2020

526

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In vitro microfluidic modelling of the human blood-brain-barrier microvasculature and testing of nanocarrier transport

Marco Campisi, Sharon W. L. Lee, Tatsuya Osaki, Luca Possenti, Clara Mattu, Giulia Adriani, Valeria Chiono, Roger D. Kamm

https://doi.org/10.4081/bse.105

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Published: 12 February 2020

2020

PDF: 520
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Tissue engineered constructs for the replacement of laboratory animals: Biomimetics and microfluidics

Maria Grazia Cascone, Luigi Lazzeri, Elisabetta Rosellini

https://doi.org/10.4081/bse.83

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Published: 11 February 2020

465

PDF: 273
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Quantification of the foreign body reaction by means of a miniaturized imaging window for intravital nonlinear microscopy

Claudio Conci, Emanuela Jacchetti, Tommaso Zandrini, Laura Sironi, Maddalena Collini, Giuseppe Chirico, Giulio Cerullo, Roberto Osellame, Manuela Teresa Raimondi

https://doi.org/10.4081/bse.106

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Published: 14 February 2020

1536

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Approaching 3R teaching in biomedical engineering

Valeria Chiono

https://doi.org/10.4081/bse.84

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Published: 11 February 2020

483

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Chitosan biopolymer: Alternative adhesion factor and scaffold matrix for 2D and 3D neuronal cultures

Donatella Di Lisa, Mariateresa Tedesco, Elena Dellacasa, Mattia Pesce, Tiziano Catelani, Paolo Massobrio, Roberto Raiteri, Sergio Martinoia, Laura Pastorino

https://doi.org/10.4081/bse.107

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Published: 14 February 2020

1985

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On the transferability of tissue engineering technologies to the design of tissue models

Gianluca Ciardelli

https://doi.org/10.4081/bse.85

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Published: 11 February 2020

370

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European regulatory framework for the clinical translation of bioprinted scaffolds and tissues

Licia Di Pietro, Alice Ravizza, Giovanni Vozzi, Andrés Diaz Lantada, Arti Ahluwalia, Carmelo De Maria

https://doi.org/10.4081/bse.108

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Published: 14 February 2020

925

PDF: 473
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Use of an in vitro model of hepatic steatosis for studying the anti-oxidant and antisteatotic effects of fucoidan polysaccharides

Zeinab El Rashed, Hala Khalife, Adriana Voci, Elena Grasselli, Laura Canesi, Ilaria Demori

https://doi.org/10.4081/bse.109

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Published: 14 February 2020

549

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Biomechanical simulations and 3D printing for endovascular device testing

Michele Conti, Stefania Marconi, Ferdinando Auricchio

https://doi.org/10.4081/bse.86

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Published: 11 February 2020

442

PDF: 268
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Computational molecular modelling as a platform for a deeper understanding of protein dynamics and rational drug design

Gianvito Grasso, Lorenzo Pallante, Jack A. Tuszynski, Umberto Morbiducci, Marco A. Deriu

https://doi.org/10.4081/bse.87

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Published: 11 February 2020

599

PDF: 280
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Effects of occupational exposure to glyphosate in winegrowers

Melissa Ferrian, Antonella Annicchiarico, Mario Oliveri, Claudio Colosio, Emanuela Corsini, Alessandra Barassi, Giuseppe Mastrangelo, Emanuela Fadda, Manuela Peruzzi, Stefano Porru

https://doi.org/10.4081/bse.110

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Published: 14 February 2020

610

PDF: 317
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Versatile electrical stimulator for providing cardiac-like electrical impulses in vitro

Stefano Gabetti, Giovanni Putame, Federica Montrone, Giuseppe Isu, Anna Marsano, Alberto Audenino, Diana Massai

https://doi.org/10.4081/bse.111

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Published: 14 February 2020

823

PDF: 347
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Characterising the current provision of education and training courses relevant to the Replacement, Reduction and Refinement (Three Rs) of animals used for scientific purposes

Adelaide Dura, Marcelle Holloway

https://doi.org/10.4081/bse.88

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Published: 11 February 2020

914

PDF: 439
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Swiss 3R Competence Centre: Promoting the 3Rs implementation

Chantra Eskes

https://doi.org/10.4081/bse.89

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Published: 11 February 2020

355

PDF: 237
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Analysis of non-animal methods and models for research in cardiovascular disease

Emanuele Gasparotti, Margherita Cioffi, Vincenzo Positano, Emanuele Vignali, Benigno Marco Fanni, Katia Capellini, Dorela Haxhiademi, Emiliano Costa, Sergio Berti, Luigi Landini, Simona Celi, Laura Gribaldo

https://doi.org/10.4081/bse.112

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Published: 14 February 2020

587

PDF: 282
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Advanced culture systems for ex vivo human vascular tissue conditioning

Gianfranco Beniamino Fiore, Simona Seminati, Lorenzo Pietro Coppadoro, Elia Pederzani, Marco Piola, Monica Soncini

https://doi.org/10.4081/bse.90

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Published: 11 February 2020

448

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Clarifying mid-brain organoids: Application of the CLARITY protocol to unperfusable samples

Chiara Magliaro, Arti Ahluwalia

https://doi.org/10.4081/bse.113

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Published: 14 February 2020

1095

PDF: 446
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Application of two in vitro methods for the toxicity test of autogenous vaccines

Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori

https://doi.org/10.4081/bse.114

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Published: 14 February 2020

603

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Refinement of laboratory animal welfare

Angelo Gazzano, Chiara Mariti

https://doi.org/10.4081/bse.91

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Published: 11 February 2020

461

PDF: 357
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Pisa Biobank and Tuscany Regional Biorepository

Francesca Nocchi, Patrizia Urciuoli, Silvia Ursino, Elisa Biagi, Simone Lapi

https://doi.org/10.4081/bse.92

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Published: 11 February 2020

493

PDF: 260
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Engineering a dynamic model of the alveolar interface for the study of aerosol deposition

Roberta Nossa, Joana Costa, Ludovica Cacopardo, Arti Ahluwalia

https://doi.org/10.4081/bse.115

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Published: 14 February 2020

676

PDF: 363
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The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa

Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga

https://doi.org/10.4081/bse.116

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Published: 14 February 2020

603

PDF: 334
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QSAR models and their practical use. The experience of Kode

Alberto Manganaro

https://doi.org/10.4081/bse.93

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Published: 11 February 2020

429

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Bioreactors as physiologicallike in vitro models

Sara Mantero, Federica Boschetti

https://doi.org/10.4081/bse.94

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Published: 11 February 2020

368

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Health monitoring program for the control of laboratory animal diseases

Chiara Romano, Andrea Cacciamali, Silvia Dotti, Riccardo Villa

https://doi.org/10.4081/bse.117

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Published: 14 February 2020

665

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For an ethics of experimentation. Moral arguments supporting 3Rs

Franco Manti

https://doi.org/10.4081/bse.95

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Published: 11 February 2020

354

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Zebrafish as an alternative method for toxicological studies

Maria Sampieri, Riccardo Villa, Silvia Dotti

https://doi.org/10.4081/bse.118

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Published: 14 February 2020

703

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Assessment of an in vitro physiological relevant model to check therapeutic strategies for glaucoma

Sara Tirendi, Stefania Vernazza, Sergio Saccà, Anna Maria Bassi

https://doi.org/10.4081/bse.120

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Published: 14 February 2020

674

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Centro 3R: Organ and tissue sharing project

Manuela Marcoli

https://doi.org/10.4081/bse.96

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Published: 11 February 2020

322

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Renewing potency assays: Moving forward from traditional methods

Francesco Nevelli

https://doi.org/10.4081/bse.97

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Published: 12 February 2020

456

PDF: 351
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SG-2: A promising lipolytic and pro-autophagic hit-compound to treat Alzheimer's disease

Massimiliano Runfola, Michele Perni, Simona Sestito, Grazia Chiellini, Michele Vendruscolo, Simona Rapposelli

https://doi.org/10.4081/bse.121

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Published: 14 February 2020

629

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In vitro models of human cardiac fibrotic tissue on bioartificial scaffolds

Alice Zoso, Irene Carmagnola, Gerardina Ruocco, Mattia Spedicati, Valeria Chiono

https://doi.org/10.4081/bse.122

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Platelet rich plasma enhancement of skin regeneration in an ex vivo human experimental model

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Neurophysiological models of animal sentience

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Reconstituted epithelial tissues and native cornea: A comparison of the influence of surfactants on ocular permeability

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Biobanking and biomolecular resource research infrastructure: The Italian node

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Hydrogel-based platforms to mimic in vivo drug diffusion: A multicenter research

Paola Petrini, Daniela Pacheco, Francesco Briatico Vangosa, Cosmin S. Butnarasu, Livia Visai, Orietta Monticelli, Laura Pastorino, Sonja Visentin

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Organoid culture systems: Products supporting one of the biggest revolutions in biological research

Ryan Conder, Leon H. Chew, Fisal Elstone, Marianne Lankhorst, Adam Añonuevo, Salvatore Simmini, Wing Chang, Allen C. Eaves, Terry E. Thomas, Sharon A. Louis

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Manufacturability and mechanical testing considerations of metallic scaffolds fabricated using selective laser melting: a review

Swee Leong Sing, Yixin Miao, Florencia Edith Wiria, Wai Yee Yeong

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Published: 30 May 2016

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Drug-free antibacterial polymers for biomedical applications

Ayesha Idrees, PatrÃcia Varela, Francesca Ruini, Jeddah Marie Vasquez, Jochen Salber, Udo Greiser, Wenxin Wang, Sean McMahon, Susanna Sartori, Gianluca Ciardelli, Valeria Chiono

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Published: 10 May 2018

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Phantoms in medicine: The case of ophthalmology

Carmelo De Maria, Sara Iorio, Francesca Montemurro, Gabriele Maria Fortunato, Michela Ori, Vittoria Raffa, Giovanni Vozzi

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Published: 8 July 2019

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APPENDIX: 188
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Abstract Book

Drug-Free Antibacterial Technology for Medical Applications - First Cambridge International Conference - December 14th, 2018 - Cambridge, UK

Valeria Chiono, Jochen Salber

https://doi.org/10.4081/bse.66

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Published: 25 February 2019

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