Vol. 2 No. 1 (2021)

Communications

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  Comparative analysis of different hydrogels for the bioprinting of 3D in vitro skeletal muscle models

  Flaminia Aliberti, Lorenza Rinvenuto, Giada Loi, Laura Benedetti, Franca Scocozza, Flavio Lorenzo Ronzoni, Maurilio Sampaolesi, Gabriella Cusella, Michele Conti, Gabriele Ceccarelli

  https://doi.org/10.4081/bse.146

  Published: 29 September 2021

  1654

  PDF: 350

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  Ink-jet printed chitosan precise patterning for engineered 2D neuronal networks

  Andrea Andolfi, Pietro Arnaldi, Donatella Di Lisa, Sergio Martinoia, Laura Pastorino

  https://doi.org/10.4081/bse.148

  Published: 29 September 2021

  1117

  PDF: 270

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  Development of in vitro 3D culture system to mimic lung cancer tissue

  Désirée Baruffaldi, Marta Canta, Candido Fabrizio Pirri, Francesca Frascella

  https://doi.org/10.4081/bse.149

  Published: 29 September 2021

  355

  PDF: 213

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  Novel 3D in vitro retina model to investigate mechanisms involved in age-related macular degeneration

  Beatrice Belgio, Sara Mantero, Federica Boschetti

  https://doi.org/10.4081/bse.150

  Published: 29 September 2021

  308

  PDF: 206

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  Optimization of primary hepatocyte isolation for the pharmacological characterization of metabotropic glutamate receptor (mGluR) subtype 5: a study on Reduction

  Clarissa Berardo, Andrea Ferrigno, Veronica Siciliano, Marta Cagna, Plinio Richelmi, Mariapia Vairetti, Laura G. Di Pasqua

  https://doi.org/10.4081/bse.151

  Published: 29 September 2021

  273

  PDF: 191

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  Coupling in silico and ex vivo porcine model for the evaluation of biomechanical impact of TEVAR

  Daniele Bianchi, Daniele Bissacco, Maurizio Domanin, Santi Trimarchi, Rodrigo Romarowski, Stefania Marconi, Ferdinando Auricchio, Michele Conti

  https://doi.org/10.4081/bse.152

  Published: 29 September 2021

  305

  PDF: 178

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  Differentiated neuroblastoma F-11 cells as an alternative in vitro model to dorsal root ganglion neurons

  Stefania Blasa, Valentina Pastori, Alessia D'Aloia, Marzia M. Lecchi

  https://doi.org/10.4081/bse.153

  Published: 29 September 2021

  624

  PDF: 298

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  Minimum performance level definition for bone plate testing according to standard: A preliminary study

  Federico A. Bologna, Mara Terzini, Andrea T. Lugas, Alberto L. Audenino

  https://doi.org/10.4081/bse.154

  Published: 29 September 2021

  331

  PDF: 261

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  Total and local experimental validation of a lumbar spine numerical model to enhance the orthopaedic management of spinal metastases

  Simone Borrelli, Giovanni Putame, Mara Terzini, Andrea Ferro, Stefano Marone, Cristina Bignardi, Alberto L. Audenino

  https://doi.org/10.4081/bse.155

  Published: 29 September 2021

  260

  PDF: 194

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  A novel in silico tool for dose assessment in cell culture nanotoxicology

  Ermes Botte, Pietro Vagaggini, Joana Costa, Lara Faccani, Ilaria Zanoni, Anna Costa, Arti Ahluwalia

  https://doi.org/10.4081/bse.156

  Published: 29 September 2021

  412

  PDF: 261

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  Superoxide dismutase 1 (SOD1) and cadmium: a three models approach to the comprehension of its neurotoxic effects

  Federica Bovio, Barbara Sciandrone, Chiara Urani, Paola Fusi, Matilde Forcella, Maria Elena Regonesi

  https://doi.org/10.4081/bse.157

  Published: 29 September 2021

  284

  PDF: 235

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  3F(eature)s model: modularity, heterogeneity and three-dimensionality to design in vitro neuronal model

  Martina Brofiga, Marietta Pisano, Mariateresa Tedesco, Francesca Callegari, Paolo Massobrio

  https://doi.org/10.4081/bse.158

  Published: 29 September 2021

  337

  PDF: 247

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  Detection of pathogens from environmental samples for the evaluation of the health status of laboratory animals

  Andrea Cacciamali, Chiara Romano, Martina Angela Checco, Riccardo Villa

  https://doi.org/10.4081/bse.159

  Published: 29 September 2021

  495

  PDF: 295

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  A programmable culture platform for stimulation and in situ sensing of lung epithelial cells

  Nicolò Cacocciola, Matteo Parmeggiani, Matteo Segantini, Alessio Verna, Désirée Baruffaldi, Simona Villata, Francesca Frascella, Simone Luigi Marasso, Giancarlo Canavese, Matteo Cocuzza, Fabrizio Candido Pirri

  https://doi.org/10.4081/bse.160

  Published: 29 September 2021

  415

  PDF: 275

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  3D printed microfluidic devices for cell culture

  Marta Canta, Désirée Baruffaldi, Ignazio Roppolo, Annalisa Chiappone, Candido F. Pirri, Francesca Frascella

  https://doi.org/10.4081/bse.161

  Published: 29 September 2021

  734

  PDF: 326

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  An osteochondral bio-engineered model to in vitro mimicking osteoarthritis

  Giorgia Cerqueni, Annachiara Scalzone, Xiao Nong Wang, Caterina Licini, Kenny Dalgarno, Ana Marina Ferreira-Duarte, Piergiorgio Gentile, Monica Mattioli Belmonte

  https://doi.org/10.4081/bse.162

  Published: 29 September 2021

  404

  PDF: 232

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  Effect of manuka honey on 5-fluorouracil chemosensitivity in colonspheres enriched with cancer stem (-like) cells

  Danila Cianciosi, Lucia Regolo, Maurizio Battino, Francesca Giampieri

  https://doi.org/10.4081/bse.163

  Published: 29 September 2021

  373

  PDF: 191

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  Targeting cancer drug resistance by modulation of ERCC1-XPF and p53 activity

  Gloria Ciniero, Francesco Gentile, Ahmed H. Elmenoufy, Emeline Cros-Perrial, Frederick G. West, Michael Weinfeld, Marco A. Deriu, Lars P. Jordheim, Jack A. Tuszynski

  https://doi.org/10.4081/bse.164

  Published: 29 September 2021

  469

  PDF: 263

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  Development and characterization of a novel human 3D model of bone metastasis from breast carcinoma in vitro cultured

  Deyanira Contartese, Francesca Salamanna, Veronica Borsari, Stefania Pagani, Maria Sartori, Lucia Martini, Giovanni Barbanti Brodano, Alessandro Gasbarrini, Milena Fini

  https://doi.org/10.4081/bse.165

  Published: 29 September 2021

  285

  PDF: 191

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  Towards reliable in vitro models. New bi-compartmental platforms for replicating tissue barriers

  Lorenzo P. Coppadoro, Elia Pederzani, Chiara Foglieni, Maria Lombardi, Gianfranco B. Fiore, Monica Soncini

  https://doi.org/10.4081/bse.166

  Published: 29 September 2021

  330

  PDF: 208

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  An in vitro enterocyte cell-like model to study Group B streptococci internalization

  Giuseppe Valerio De Gaetano, Germana Lentini, Roberta Galbo, Francesco Coppolino, Agata Famà, Giuseppe Teti

  https://doi.org/10.4081/bse.167

  Published: 29 September 2021

  799

  PDF: 202

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  Bioprinting for osteosarcoma model: Methodological aspects and experimental applications

  Elena Delgrosso, Gaia Martina Sarcinelli, Federica Riva, Federica Riva, Franca Scocozza, Michele Conti, Ian Postuma, Silva Bortolussi, Cinzia Ferrari

  https://doi.org/10.4081/bse.168

  Published: 29 September 2021

  937

  PDF: 295

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  Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer

  Stefania Forciniti, Marta Cavo, Ilaria Dando, Elisa Dalla Pozza, Marta Palmieri, Loretta L. del Mercato

  https://doi.org/10.4081/bse.169

  Published: 29 September 2021

  627

  PDF: 237

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  Comparing genomic profiles of tumour and peritumoral biopsies to find new possible biomarkers for glioblastoma therapy.

  Martina Giambra, Eleonora Messuti, Serena Redaelli, Andrea Di Cristofori, Angela Bentivegna

  https://doi.org/10.4081/bse.170

  Published: 29 September 2021

  588

  PDF: 175

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  Light-based 3D printing of functional polydimethylsiloxane- based microfluidic chips

  Gustavo A. Gonzalez, Annalisa Chiappone, Kurt Dietliker, Pirri C. Fabrizio, Ignazio Roppolo

  https://doi.org/10.4081/bse.171

  Published: 29 September 2021

  652

  PDF: 341

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  Drug-induced hepatotoxicity studied in a 3D, in vitro model of the liver

  Giuseppe Guagliano, Manuela Legnardim, Cristina Volpini, Nora Bloise, Silvia Dotti, Riccardo Villa, Livia Visai, Paola Petrini

  https://doi.org/10.4081/bse.172

  Published: 29 September 2021

  665

  PDF: 193

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  Engineering magneto-responsive core-shell microbeads for mimicking peristalsis and alveolar breathing in vitro

  Nicole Guazzelli, Ludovica Cacopardo, Arti Ahluwalia

  https://doi.org/10.4081/bse.173

  Published: 29 September 2021

  693

  PDF: 223

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  An in vitro lung biomimetic model

  Michela Licciardello, Gianluca Ciardelli, Chiara Tonda-Turo

  https://doi.org/10.4081/bse.174

  Published: 29 September 2021

  617

  PDF: 209

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  Patient-specific modelling for the assessment of the hemodynamics risk of failure in endovascular aneurysm repair

  Maurizio Lodi Rizzini, Paola Tasso, Anastasios Raptis, Miltiadis Matsagkas, Diego Gallo, Michalis Xenos, Umberto Morbiducci

  https://doi.org/10.4081/bse.175

  Published: 29 September 2021

  685

  PDF: 230

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  Development of a multiscale testing method for the reduction of soft biological tissues waste during mechanical characterization

  Andrea T. Lugas, Gianpaolo Serino, Mara Terzini, Cristina Bignardi, Alberto L. Audenino

  https://doi.org/10.4081/bse.176

  Published: 29 September 2021

  652

  PDF: 208

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  Human tissue culture of osteochondral defect: An advanced in vitro model

  Melania Maglio, Matilde Tschon, Stefania Pagani, Leonardo Vivarelli, Marco Govoni, Martina Rocchi, Alessandro Mazzotta, Lucia Martini, Dante Dallari, Milena Fini

  https://doi.org/10.4081/bse.177

  Published: 29 September 2021

  598

  PDF: 169

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  Innovative 3D proteome-wide scale identification of ALKBH5 target for MV1035 small molecule able to reduce migration and invasiveness in U87 glioblastoma cell lines by SPILLO-PBSS

  Alessio Malacrida, Mirko Rivara, Omar Ben Mariem, Alessandro Di Domizio, Giacomo Cislaghi, Mariarosaria Miloso, Valentina Zuliani, Gabriella Nicolini

  https://doi.org/10.4081/bse.178

  Published: 29 September 2021

  676

  PDF: 210

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  Toward scalable in vitro models: a novel experimental and computational pipeline for the identification of cellular metabolic parameters

  Piera Mancini, Ermes Botte, Chiara Magliaro, Arti Ahluwalia

  https://doi.org/10.4081/bse.179

  Published: 29 September 2021

  592

  PDF: 193

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  View the meniscus: MicroCT strategies for enhancing microstructure visualization

  Gregorio Marchiori, Melania Maglio, Lucia Martini, Andrea Visani, Stefano Zaffagnini, Milena Fini

  https://doi.org/10.4081/bse.180

  Published: 29 September 2021

  248

  PDF: 164

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  Recellularization of decellularized porcine caval veins

  Maria Stefania Massaro, Richard Pálek, Jáchym Rosendorf, Anna Malečková, Lenka Červenková, Roshan K. Singh, Robert Polák, Václav Liška, Vladimíra Moulisová

  https://doi.org/10.4081/bse.181

  Published: 29 September 2021

  333

  PDF: 207

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  V-ATPase as a mediator of treatment resistance in Glioblastoma Multiforme: an in vitro study to investigate new therapeutic strategies

  Eleonora Messuti, Martina Giambra, Serena Redaelli, Andrea Di Cristofori, Carlo Giussani, Angela Bentivegna

  https://doi.org/10.4081/bse.182

  Published: 29 September 2021

  298

  PDF: 189

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  Elucidating molecular connection between IAHSP onset and Alsin protein by means of homology modelling and molecular dynamics

  Marcello Miceli, Cecile Exertier, Beatrice Vallone, Marco Cavaglià, Marco A. Deriu

  https://doi.org/10.4081/bse.183

  Published: 29 September 2021

  362

  PDF: 222

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  Light processable starch hydrogels

  Camilla Noè, Chiara Tonda-Turo, Annalisa Chiappone, Marco Sangermano, Minna Hakkarainen

  https://doi.org/10.4081/bse.184

  Published: 29 September 2021

  261

  PDF: 187

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  Cadmium elicits alterations in mitochondrial morphology and functionality in C3H10T1/2Cl8 mouse fibroblast cell

  Monica Oldani, Chiara Milani, Federico Gaboardi, Marta Manzoni, Anna M. Villa, Federico M. Stefanini, Pasquale Melchioretto, Eugenio Monti, Matilde Forcella, Chiara Urani, Paola Fusi

  https://doi.org/10.4081/bse.185

  Published: 29 September 2021

  249

  PDF: 172

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  Angiogenesis biomarkers detection on a polymeric 3D printed device

  Gianluca Palmara, Alessandro Chiadò, Annalisa Chiappone, Fabrizio Pirri, Ignazio Roppolo, Francesca Frascella

  https://doi.org/10.4081/bse.186

  Published: 29 September 2021

  373

  PDF: 217

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  A novel in vitro culture system for the generation of controlled hydrodinamic stimuli

  Elia Pederzani, Lorenzo P. Coppadoro, Chiara Foglieni, Maria Lombardi, Monica Soncini, Gianfranco B. Fiore

  https://doi.org/10.4081/bse.187

  Published: 29 September 2021

  323

  PDF: 310

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  Simulated models for testing performance of a radiofrequency ablation device for spine tumors

  Federica Rusinà, Alice Ravizza, Stefano Pasquino, Mario Muto

  https://doi.org/10.4081/bse.188

  Published: 29 September 2021

  371

  PDF: 199

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  Chilled storage of zebrafish embryos: Development of an efficient protocol

  Maria Sampieri, Erika Molica Colella, Silvia Dotti

  https://doi.org/10.4081/bse.189

  Published: 29 September 2021

  299

  PDF: 243

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  In vitro multi-level approaches to study cadmium neurotoxicity

  Marta Scrivani, Matilde Forcella, Federica Bovio, Alessia Bogni, Marco Fabbri, Laura Gribaldo, Sergio Andò, Pasquale Melchioretto, Maria Tringali, Paola Fusi, Chiara Urani

  https://doi.org/10.4081/bse.190

  Published: 29 September 2021

  265

  PDF: 222

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  Design of a contamination-free microfluidic device for Electrolyte-Gated Organic Field-Effect Transistor (EGOFET) biosensors

  Matteo Segantini, Matteo Parmeggiani, Alberto Ballesio, Francesca Frascella, Gianluca Palmara, Matteo Cocuzza, Candido Fabrizio Pirri, Simone Luigi Marasso

  https://doi.org/10.4081/bse.191

  Published: 29 September 2021

  348

  PDF: 317

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  PDMS Substrates with tunable stiffness for cardiac mechanobiology investigation: A nanoindentation study

  Gianpaolo Serino, Andrea T. Lugas, Giacomo Bernava, Sara Ragazzini, Stefano Gabetti, Mara Terzini, Umberto Morbiducci, Alberto Audenino, Maurizio Pesce, Diana Massai

  https://doi.org/10.4081/bse.192

  Published: 29 September 2021

  416

  PDF: 355

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  3D in vitro model of the pancreatic acino-ductal unit through additive manufacturing technology

  Viola Sgarminato, Chiara Tonda-Turo, Gianluca Ciardelli

  https://doi.org/10.4081/bse.194

  Published: 29 September 2021

  394

  PDF: 212

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  Machine learning approaches as an alternative to traditional statistical methods in cardiovascular risk prediction

  Michela Sperti, Fabrizio D'Ascenzo, Luca Navarini, Giacomo Di Benedetto, Antonella Afeltra, Roberto Giacomelli, Marco A. Deriu

  https://doi.org/10.4081/bse.195

  Published: 29 September 2021

  384

  PDF: 217

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  A compact in vitro test bench for cardiovascular flow analysis

  Elena Torta, Giuseppe Carlo Alp Caridi, Claudio Chiastra, Diego Gallo, Umberto Morbiducci

  https://doi.org/10.4081/bse.196

  Published: 29 September 2021

  412

  PDF: 267

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  Video tracking analysis of behavioral scores: The Finnover experience

  Hanna Trebesova, Federica Turrini, Guendalina Olivero, Valentina Orlandi, Dario Donno, Gabriele Beccaro, Raffaella Boggia, Anna Pittaluga, Massimo Grilli

  https://doi.org/10.4081/bse.197

  Published: 29 September 2021

  293

  PDF: 289

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  Nuclear receptor modulators: Catching information by machine learning

  Cecile Valsecchi, Francesca Grisoni, Viviana Consonni, Davide Ballabio, Roberto Todeschini

  https://doi.org/10.4081/bse.198

  Published: 29 September 2021

  312

  PDF: 182

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  In silico experiments as a tool to reduce preclinical tests of magnetic hyperthermia

  Marta Vicentini, Marta Vassallo, Riccardo Ferrero, Alessandra Manzin

  https://doi.org/10.4081/bse.199

  Published: 29 September 2021

  326

  PDF: 193

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  Electrostimulation of a 3D in vitro skin model to activate wound healing

  Simona Villata, Lucia Napione, Désirée Baruffaldi, Christine Nardini, Francesca Frascella, Fabrizio Pirri

  https://doi.org/10.4081/bse.200

  Published: 29 September 2021

  570

  PDF: 285

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  Visible light-induced cross-linking of unmodified gelatin with PEGDA for DLP-3D printable hydrogels

  Michael Zanon, Désirée Baruffaldi, Marco Sangermano, Candido Fabrizio Pirri, Francesca Frascella, Annalisa Chiappone

  https://doi.org/10.4081/bse.201

  Published: 29 September 2021

  609

  PDF: 392

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  In silico investigation of molecular interactions of volatile anesthetics: effects on phospholipid membranes and subcellular targets

  Eric A. Zizzi, Marco Cavaglià, Marco A. Deriu, Jack A. Tuszynski

  https://doi.org/10.4081/bse.202

  Published: 29 September 2021

  333

  PDF: 207

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  Polyvinyl alcohol/cellulose hydrogel as possible corneal stroma substitute in drug permeation tests

  Erica Zucchetti, Leonardo Ling, Daniela Monti, Patrizia Chetoni, Silvia Tampucci, Susi Burgalassi

  https://doi.org/10.4081/bse.203

  Published: 29 September 2021

  325

  PDF: 205

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