PDMS Substrates with tunable stiffness for cardiac mechanobiology investigation: A nanoindentation study


https://doi.org/10.4081/bse.192
Vol. 2 No. 1 (2021)
Published: 29 September 2021
Nanoindentation, mechanobiology, PDMS, cardiac tissue, cardiac fibrosis
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Authors

  • Gianpaolo Serino
    gianpaolo.serino@polito.it
    PolitoBIOMed Lab, Departement of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.
  • Andrea T. Lugas PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.
  • Giacomo Bernava Centro Cardiologico Monzino, Milan, Italy.
  • Sara Ragazzini Centro Cardiologico Monzino, Milan, Italy.
  • Stefano Gabetti PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.
  • Mara Terzini PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.
  • Umberto Morbiducci PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; 2Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research;, Italy.
  • Alberto Audenino PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.
  • Maurizio Pesce Centro Cardiologico Monzino, Milan, Italy.
  • Diana Massai PolitoBIOMed Lab, Dept. of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino; Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Italy.

Micromechanical characterization by nanoindentation of PDMS substrates for cardiac mechanobiology studies.


Serino, G., Lugas, A. T., Bernava, G., Ragazzini, S., Gabetti, S., Terzini, M., Morbiducci, U., Audenino, A., Pesce, M., & Massai, D. (2021). PDMS Substrates with tunable stiffness for cardiac mechanobiology investigation: A nanoindentation study. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.192

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