Human tissue culture of osteochondral defect: An advanced in vitro model


Published: 29 September 2021
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Authors

  • Melania Maglio IRCCS Istituto Ortopedico Rizzoli, Complex Structure Surgical Sciences and Technologies, Bologna, Italy.
  • Matilde Tschon IRCCS Istituto Ortopedico Rizzoli, Complex Structure Surgical Sciences and Technologies, Bologna, Italy.
  • Stefania Pagani IRCCS Istituto Ortopedico Rizzoli, Complex Structure Surgical Sciences and Technologies, Bologna, Italy.
  • Leonardo Vivarelli IRCCS Istituto Ortopedico Rizzoli, Reconstructive Orthopaedic Surgery and Innovative Techniques - Musculoskeletal Tissue Bank, Bologna, Italy.
  • Marco Govoni IRCCS Istituto Ortopedico Rizzoli, Reconstructive Orthopaedic Surgery and Innovative Techniques - Musculoskeletal Tissue Bank, Bologna, Italy.
  • Martina Rocchi IRCCS Istituto Ortopedico Rizzoli, Reconstructive Orthopaedic Surgery and Innovative Techniques - Musculoskeletal Tissue Bank, Bologna, Italy.
  • Alessandro Mazzotta IRCCS Istituto Ortopedico Rizzoli, Reconstructive Orthopaedic Surgery and Innovative Techniques - Musculoskeletal Tissue Bank, Bologna, Italy.
  • Lucia Martini IRCCS Istituto Ortopedico Rizzoli, Complex Structure Surgical Sciences and Technologies, Bologna, Italy.
  • Dante Dallari IRCCS Istituto Ortopedico Rizzoli, Reconstructive Orthopaedic Surgery and Innovative Techniques - Musculoskeletal Tissue Bank, Bologna, Italy.
  • Milena Fini IRCCS Istituto Ortopedico Rizzoli, Complex Structure Surgical Sciences and Technologies, Bologna, Italy.

The optimization of advanced in vitro models is essential for the development of alternative methods. The in vitro study of osteochondral regeneration still has numerous limitations and wide scope for exploration.


Maglio, M., Tschon, M., Pagani, S., Vivarelli, L., Govoni, M., Rocchi, M., Mazzotta, A., Martini, L., Dallari, D., & Fini, M. (2021). Human tissue culture of osteochondral defect: An advanced <em>in vitro</em> model. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.177

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