https://doi.org/10.4081/bse.166
Towards reliable in vitro models. New bi-compartmental platforms for replicating tissue barriers
Published: 29 September 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
In vitro cell cultures represent a widespread methodology for pathophysiology studies with a high benefit/cost ratio. We have developed and are validating TToP, a novel, versatile, and scalable culture system allowing compartmentalized cell/tissue cultures with the aim of mimicking the human pathophysiological microenvironment of tissue barriers.
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Astashkina A, Mann B, Grainger DW. A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity. Pharmacol Ther 2012;134:82-106.
Walsh III D.I. Kong DS, Murthy SK, Carr PS. Enabling Microfluidics: from Clean Rooms to Makerspaces. Trends Biotechnol2017;35:383-92.
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How to Cite
Coppadoro, L. P., Pederzani, E., Foglieni, C., Lombardi, M., Fiore, G. B., & Soncini, M. (2021). Towards reliable <em>in vitro</em> models. New bi-compartmental platforms for replicating tissue barriers. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.166
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