Development and characterization of a novel human 3D model of bone metastasis from breast carcinoma in vitro cultured

Published: 29 September 2021
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Breast cancer frequently metastasizes to the skeleton causing significant morbidity. Here, we set-up a novel and advanced ex vivo model by using fresh tissue from human vertebral bone metastasis from breast carcinoma patients able to retain the tumor microenvironment and tumor cells heterogeneity.

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Contartese, D., Salamanna, F., Borsari, V., Pagani, S., Sartori, M., Martini, L., … Fini, M. (2021). Development and characterization of a novel human 3D model of bone metastasis from breast carcinoma <em>in vitro</em> cultured. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.165

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