https://doi.org/10.4081/bse.159

Detection of pathogens from environmental samples for the evaluation of the health status of laboratory animals

Vol. 2 No. 1 (2021)
Published: 29 September 2021
Health surveillance, 3R's principle, rodents' breeding, environmental samples, molecular analysis
Abstract Views: 509
PDF: 308
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Authors

Andrea Cacciamali
andrea.cacciamali@izsler.it
IZSLER - Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna - National Reference Center for Alternative Methods, Welfare and Care of the Laboratory Animals, Brescia, Italy.
Chiara Romano
IZSLER - Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna - National Reference Center for Alternative Methods, Welfare and Care of the Laboratory Animals, Brescia, Italy.
Martina Angela Checco
IZSLER - Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna - National Reference Center for Alternative Methods, Welfare and Care of the Laboratory Animals, Brescia, Italy.
Riccardo Villa
IZSLER - Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna - National Reference Center for Alternative Methods, Welfare and Care of the Laboratory Animals, Brescia, Italy.

Pathogens present in the environment are the biggest source of diseases and epidemics in the breeding of laboratory animals. The presence of microorganisms, in fact, can critically influence the animal health status and consequently the validity and reproducibility of experimental data. In accordance with the 3Rs principle, this study fits into the Refinement and Reduction concepts. The development of a health surveillance plan on environmental material from animal housing would have an important impact not only on maintaining an adequate state of health and on the generation of quality experimental data, but also on reducing the number of animals to be sacrificed.

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How to Cite

Cacciamali, A., Romano, C., Checco, M. A., & Villa, R. (2021). Detection of pathogens from environmental samples for the evaluation of the health status of laboratory animals. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.159

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