Development of in vitro 3D culture system to mimic lung cancer tissue


Published: 29 September 2021
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Authors

  • Désirée Baruffaldi Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy.
  • Marta Canta PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy.
  • Candido Fabrizio Pirri Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin; Center for Sustainable Future Technologies @Polito, Istituto Italiano di Tecnologia, Turin, Italy.
  • Francesca Frascella Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy.

A 3D culture system based on a photocurable matrix has been developed. The aim is to create a 3D printable platform mimicking lung cancer tissue, to study tumor microenvironment evolution, in terms of structural (architecture) and molecular (signalling) components.


Baruffaldi, D., Canta, M., Pirri, C. F., & Frascella, F. (2021). Development of <em>in vitro</em> 3D culture system to mimic lung cancer tissue. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.149

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