https://doi.org/10.4081/bse.139
IVTech: The next generation of in vitro models
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In vitro cell cultures are often proposed as “Alternatives†to animal models, but they are still inadequate to reproduce the human pathophysiology. This is mainly due to the technological limitations of the standard equipment used in cell culture laboratories, such as the lack of a 3D micro-architecture, the static environment and the absence of cross talk between different tissues. These limitations cause the poor predictivity of a standard in-vitro model, if compared with the human reality.
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