https://www.pagepress.org/technology/bioadv <p><strong>BioMaterials Advances&nbsp;</strong>is an Open Access, online-only, peer-reviewed journal that publishes original papers, review papers and notes about all aspects of the science of biomaterials. A biomaterial is now defined as "A material or a combination of materials intended to interface with biological systems"; it can be originated either from nature or synthesized in the laboratory. The journal aims to be relevant in the broad range of biological, physical and chemical sciences related to the design and engineering of biomaterials and all the disciplines in which they are used.</p> <h1>Announcement of closure</h1> <p><strong>BioMaterials Advances</strong> is no longer open to new submissions. All papers that have been published will be permanently accessible under the terms of open access, at: <a href="https://www.pagepress.org/technology/index.php/bioadv/issue/archive">https://www.pagepress.org/technology/index.php/bioadv/issue/archive</a>.<br><br> PAGEPress would like to thank the Editors-in-Chief, Prof. Xiaoming Li, Huiqi Xie and the Editorial Board for all their efforts over the past years.<br><br> Unfortunately, the number of authors in this field contributing to the journal was not as high as expected.</p> PAGEPress Scientific Publications, Pavia, Italy en-US BioMaterials Advances <p><strong>PAGEPress</strong> has chosen to apply the <a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a> (CC BY-NC 4.0) to all manuscripts to be published.</p> https://www.pagepress.org/technology/bioadv/article/view/63 <p>The exploration of bone repair materials has been continuously carried out. After several decades of development, bone repair materials have experienced from traditional ceramics, metals and polymers to modern smart hydrogels and multifunctional composite materials, <em>etc</em>. At the same time of designing and preparing the novel materials, more and more attention has been paid to their osteogenesis mechanism and immune response. The development of next generation of bone repair materials requires the comprehensive consideration of a combination of many related factors. This article reviews the research status and the progress of bone repair materials from the three aspects, current most-used types, bioactive mechanism and updated related investigations. Finally, several research points that are crucial for the further development of bone repairs are proposed in the conclusion and perspectives part.</p> Yuqi He Wei He Yubo Fan Xiaoming Li Copyright (c) 2019 Yuqi He, Wei He, Yubo Fan, Xiaoming Li 2019-02-21 2019-02-21 2 1 10.4081/bioadv.2019.63