PNEI REVIEW is the journal published by the Italian Society of Psychoneuroendocrineimmunology (SIPNEI), a scientific inter-professional association promoting the study and care of the human being as a whole. The aim of the journal is to support the unity of the knowledge on human beings by overcoming the barriers that separate the different disciplines. The interdisciplinary program of PNEI REVIEW is implemented by hosting articles that are written in a scientific and yet clear language explaining and investigating the functioning of the human body both in health and disease. A particular emphasis is given to the bi-directional relationships between the psyche and the biological systems within the social and environmental context. Along with this scientific program, PNEI REVIEWprovides also more clinical and therapeutic focused articles and reviews with particular regard to the new models of prevention and integrative care of human health. The languages are Italian and English. Each issue hosts a monograph, decided by the Board, and other articles that will be subjected to the anonymous peer-review process.