Hyaluronic acid injection as functional adjuvant therapy in menopausal vulvovaginal symptoms - preliminary report


Submitted: 11 July 2016
Accepted: 11 July 2016
Published: 15 June 2016
Abstract Views: 768
PDF: 838
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Objective: Aim of the study is to evaluate the role of vulvovaginal injection of a cross-linked HA in patients surgically treated for cancer affected by vulvovaginal symptomatology. Methods: 23 post menopausal patients treated for endometrial cancer with vulvovaginal symptoms were treated. We performed multiple spots injections of 1ml HA with 30Gx1/2 in needle (T1), repeated after 3 months (T2). Self-evaluation using a visual analog scale and investigators evaluation were recorded one month after each treatment. Results: After T1, improvement in vulvovaginal dryness, vulval itching, burning and dyspareunia were reported. At T2, further reduction of symptoms. No side effects were recorded. Conclusions: HA injection is a new, effective adjuvant therapy of postmenopausal vulvovaginal symptoms (above in women after cancer, with hormonal treatment not recommended).


Bogliatto, F., Leidi, L., & Miletta, M. (2016). Hyaluronic acid injection as functional adjuvant therapy in menopausal vulvovaginal symptoms - preliminary report. Working Paper of Public Health, 5(1). https://doi.org/10.4081/wpph.2016.6694

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