First case report of Stevens-Johnson syndrome complicated with macrophage activation syndrome

Huasong Zeng; Xiangyuan Chen

doi:10.4081/rr.2009.e9

First case report of Stevens-Johnson syndrome complicated with macrophage activation syndrome

https://doi.org/10.4081/rr.2009.e9

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Vol. 1 No. 1 (2009)

Submitted: 22 April 2009
Accepted: 5 October 2009

Published: 17 November 2009

Stevens-Johnson Syndrome, Macrophage activiateion syndrome

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Authors

Stevens-Johnson syndrome (SJS) is a complex immunological syndrome with high morbidity and mortality and characterized by acute blistering affecting the skin and at least two mucous membranes. Macrophage activation syndrome (MAS) is a severe, potentially life-threatening syndrome that often occurs in children and adults with autoimmune disease, especially systemic-onset juvenile idiopathic arthritis or adult-onset Still’s disease. This case report highlights the potential risks of SJS developing into MAS, and suggests that rapid diagnosis and treatment are essential to achieving favorable outcomes.

Huasong Zeng

HS.Zeng, MD,PhD, Department of Allergy, Immunology and Rheumatology, Guangzhou Children’s Hospital, Guangzhou, China.

Xiangyuan Chen

Department of Allergy, Immunology and Rheumatology, Guangzhou Children’s hospital .

post-graduate student,resident

Supporting Agencies

Zeng, H., & Chen, X. (2009). First case report of Stevens-Johnson syndrome complicated with macrophage activation syndrome. Rheumatology Reports, 1(1), e9. https://doi.org/10.4081/rr.2009.e9