Giant cell arteritis and systemic sclerosis: a rare overlap syndrome


Submitted: 18 July 2014
Accepted: 27 August 2014
Published: 16 September 2014
Abstract Views: 1922
PDF: 876
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Authors

  • Antonios Psarras Clinical Immunology Unit, Second Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
  • Konstantinos Tselios Clinical Immunology Unit, Second Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
  • Ioannis Gkougkourelas Clinical Immunology Unit, Second Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
  • Alexandros Sarantopoulos Clinical Immunology Unit, Second Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
  • Panagiota Boura Clinical Immunology Unit, Second Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
Systemic sclerosis (SSc) is a connective tissue disease which is characterized by endothelium dysfunction, inflammation and fibrosis. Although scleroderma is often presented as an overlap syndrome with other autoimmune rheumatic diseases, the development of large vessel vasculitis in patients with SSc is considered extremely rare, since only three case reports have thus far been reported in English literature. Herein, we report a 65-year-old woman with a long-standing history of systemic sclerosis who developed giant cell arteritis, eight years after initial diagnosis.

Supporting Agencies


Psarras, A., Tselios, K., Gkougkourelas, I., Sarantopoulos, A., & Boura, P. (2014). Giant cell arteritis and systemic sclerosis: a rare overlap syndrome. Rheumatology Reports, 6(1). https://doi.org/10.4081/rr.2014.5558

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