https://www.pagepress.org/journals/pcr <p><strong>Pre-Clinical Research </strong>publishes peer-reviewed original research articles and reviews from the pre-clinical phases of drug discovery, i.e. from concept to animal research. The journal accepts articles from universities and research organizations and aims to provide a platform for young drug discovery researchers. This journal is open to the public and encourages readers to express themselves through letters to the editor.<br />The editorial board members were chosen for their distinguished track record in preclinical drug discovery as well as their commitment to publishing high-quality work. In order to publish a standard journal, a keen, unbiased, and rapid process is established. The <strong>Pre-Clinical Research</strong> journal is free to readers, and the publisher has decided not to charge authors either.</p> PAGEPress Scientific Publications, Pavia, Italy en-US Pre-Clinical Research 2975-0180 <p><strong>PAGEPress</strong> has chosen to apply the <a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a> (CC BY-NC 4.0) to all manuscripts to be published.</p> https://www.pagepress.org/journals/pcr/article/view/9741 <p>As a result of the emergence of the Coronavirus Disease 2019 (COVID-19) outbreak caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in the Chinese city of Wuhan, a situation of socio-economic crisis and profound psychological distress rapidly occurred worldwide. Various psychological problems and important consequences in terms of mental health, including stress, anxiety, depression, frustration, and uncertainty during the COVID-19 outbreak, emerged progressively. The COVID-19 outbreak has a widespread impact on the economy, psyche, and daily living of the public. The pandemic situation of COVID-19 had one of the most challenging impacts on education in our nation’s history. The study aimed to gather comprehensive data on how the COVID-19 lockdown and its effects have affected students' overall well-being and mental health. By assessing their knowledge, attitude, and preventive practices towards the virus, as well as evaluating the psychological impact, such as fear, depression, and anxiety, we can gain valuable insights into the challenges faced by students during this unprecedented time.</p> Sree Lakshmi Namburu Veeresh Babu Pratap Gayathri Mudapally Dharani Tumu Harika Koona Javali Pothunaka Copyright (c) 2024 the Author(s) http://creativecommons.org/licenses/by-nc/4.0 2024-06-20 2024-06-20 2 10.4081/pcr.2024.9741