Featured Articles

Published: 03-12-2024

The Journal of Nucleic Acids Investigation (JNAI) is an Open Access, peer-reviewed journal that publishes original articles, letters, protocols, and reviews on all aspects of nucleic acids pre-clinical and translational research.

microRNAs and cancer

MicroRNAs, SNPs and cancer

Angela V. Vitale, Huiping Tan, Peng Jin

https://doi.org/10.4081/jnai.2236

4301

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MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer

Daniela Asslaber, Josefina Piñón Hofbauer, Richard Greil, Alexander Egle

https://doi.org/10.4081/jnai.2130

3885

PDF: 610

HTML: 3276
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Expression of microRNA during bovine adipogenesis

Scott L. Pratt, T. Ashley Burns, Erin Curry, Susan K. Duckett

https://doi.org/10.4081/jnai.1872

7476

PDF: 0

HTML: 5451

Supplementary data table: 0
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Non-coding RNAs and cancer: microRNAs and beyond

Rachel Marie Raia, George Adrian Calin

https://doi.org/10.4081/jnai.2305

4128

PDF: 626

HTML: 2051
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Molecular markers for prediction of risk of radiation-related injury to normal tissue

Marco Ghilotti, Marco Alessandro Pierotti, Manuela Gariboldi

https://doi.org/10.4081/jnai.2055

4711

PDF: 735

HTML: 9070
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Online resources for microRNA analysis

Panagiotis Alexiou, Manolis Maragkakis, Artemis G Hatzigeorgiou

e4

https://doi.org/10.4081/jnai.2161

4123

PDF: 526

HTML: 1588
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MicroRNAs in mouse models of lymphoid malignancies

Nicola A.O. Zanesi, Yuri Pekarsky, Francesco Trapasso, George Calin, Carlo M. Croce

https://doi.org/10.4081/jnai.1727

1553

PDF: 662

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Therapeutic implications of microRNAs in human cancer

Michael Rossbach

https://doi.org/10.4081/jnai.2200

5925

PDF: 1132

HTML: 2278
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Role of microRNAs in solid tumors

Rie Hamano, Hideshi Ishii, Hiroshi Miyata, Yuichiro Doki, Masaki Mori

https://doi.org/10.4081/jnai.2164

11203

PDF: 686

HTML: 9324
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Body fluid micro(mi)RNAs as biomarkers for human cancer

Edward R. Sauter, Neel Patel

https://doi.org/10.4081/jnai.2160

5071

PDF: 814

HTML: 2335
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Role of microRNAs in the molecular diagnosis of cancer

Simona Giglio, Andrea Vecchione

https://doi.org/10.4081/jnai.1659

1176

PDF: 617

HTML: 8204
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Articles

A new entropy model for RNA: part I. A critique of the standard Jacobson-Stockmayer model applied to multiple cross links

Wayne Dawson, Kenji Yamamoto, Gota Kawai

https://doi.org/10.4081/jnai.2650

3299

PDF: 603

APPENDICES: 2
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A new entropy model for RNA: part II. Persistence-related entropic contributions to RNA secondary structure free energy calculations

Wayne Dawson, Kenji Yamamoto, Kentaro Shimizu, Gota Kawai

https://doi.org/10.4081/jnai.2651

4018

PDF: 682

APPENDIX: 251
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A new entropy model for RNA: part III. Is the folding free energy landscape of RNA funnel shaped?

Wayne Dawson, Toshikuni Takai, Nobuharu Ito, Kentaro Shimizu, Gota Kawai

https://doi.org/10.4081/jnai.2652

5046

PDF: 985
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A new entropy model for RNA: part IV, The Minimum Free Energy (mFE) and the thermodynamically most-probable folding pathway (TMPFP)

Wayne Dawson, Gota Kawai

https://doi.org/10.4081/jnai.2653

1536

PDF: 793

Supplement S2: Methods: the vsfold5 algorithm: 0

Prediction of RNA Pseudoknots Using Heuristic Modeling with Mapping and Sequential Folding: 0
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A new entropy model for RNA: part V, Incorporating the Flory-Huggins model in structure prediction and folding

Wayne Dawson, Gota Kawai

https://doi.org/10.4081/jnai.2657

1549

PDF: 1167
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Computational prediction of candidate miRNAs and their targets from the completed Linum ussitatissimum genome and EST database

Tiffanie Y. Moss, Christopher A. Cullis

https://doi.org/10.4081/jnai.4150

3483

PDF: 698

Supplementary Files: 1
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The effect of in vitro exposure to antisense oligonucleotides on macrophage morphology and function

Ann Brasey, Raouf Igue, Loubna Djemame, Serge Séguin, Paolo Renzi, Nicolay Ferrari, Rosanne Seguin

https://doi.org/10.4081/jnai.3515

1568

PDF: 597
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Unusual 5'-regulatory structure and regulation of the murine Mlc1 gene: lack of promoter-specific functional elements

Darja Henseler, Jonathan D. Turner, Matthias Eckhardt, Maaike van der Mark, Yanina Revsin, Michelle K. Lin, Thorsten Kranz, Claude Muller, Jobst Meyer

https://doi.org/10.4081/jnai.2314

1915

PDF: 654
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Development of network inference among LexA/RecA-dependent manner genes in the SOS response

Sachiyo Aburatani

https://doi.org/10.4081/jnai.1871

1953

PDF: 530

HTML: 1330

Supplementary data table: 0
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Silencing of hpv16 e6 and e7 oncogenic activities by small interference RNA induces autophagy and apoptosis in human cervical cancer cells

Jonathan Salazar-León, Fabiola Reyes-Román, Angélica Meneses-Acosta, Horacio Merchant, Alfredo Lagunas-Martínez, Elizabeth Meda-Monzón, María Luisa Pita-López, Claudia Gómez-Cerón, Victor Hugo Bermúdez-Morales, Vicente Madrid-Marina, Oscar Peralta-Zaragoza

https://doi.org/10.4081/jnai.2583

2848

PDF: 749

Supplementary Table 1: 0

Supplementary Figure 1: 0
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GyrB vs. 16s rRna sequencing for the identification of Campylobacter jejuni, Campylobacter coli, and Campylobacter lari

Nereus William Gunther IV, Jonnee Almond, Xianghe Yan, David S Needleman

https://doi.org/10.4081/jnai.2303

5180

PDF: 724

HTML: 2481
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FHIT suppresses inflammatory carcinogenic activity by inducing apoptosis in esophageal epithelial cells

Koshi Mimori, Takehiko Yokobori, Masaaki Iwatsuki, Tomoya Sudo, Fumiaki Tanaka, Kohei Shibata, Hideshi Ishii, Masaki Mori

https://doi.org/10.4081/jnai.1460

857

PDF: 578

HTML: 1409
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A novel detection method for heteroduplex DNA using carbodiimide-induced interrupted primer extension

Tania Tabone, Richard Cotton, Ninan Mathew, J. Des Parkin, Judy Savige

https://doi.org/10.4081/jnai.1577

1142

PDF: 543

HTML: 11434
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Robust hybridization-based genotyping probes for HPV 6, 11, 16 and 18 obtained via in vitro selection

Ivan B. Brukner, Anne-Marie Larose, Izabella Gorska-Flipot, Maja Krajinovic, Damian Labuda

https://doi.org/10.4081/jnai.1491

1368

PDF: 644

HTML: 4538
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The mitochondrial housekeeping gene 16S is inappropriate as an internal standard in comparative studies of rare mitochondrial transcripts using S1-nuclease protection assays

Sandra Ebert, Line Breumlund, Roland Nau, Uwe Michel

https://doi.org/10.4081/jnai.1588

1409

PDF: 524

HTML: 5149
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Reviews

P53 and microRNAs in chronic lymphocytic leukemia

Johannes Bloehdorn, Christian Langer, Hartmut Döhner, Thorsten Zenz, Stephan Stilgenbauer

https://doi.org/10.4081/jnai.2414

5375

PDF: 544

HTML: 4381
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HER2 splice variants and their relevance in breast cancer

Marianna Sasso, Francesca Bianchi, Valentina Ciravolo, Elda Tagliabue, Manuela Campiglio

https://doi.org/10.4081/jnai.2454

3488

PDF: 1308
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High mobility group A-interacting proteins in cancer: focus on chromobox protein homolog 7, homeodomain interacting protein kinase 2 and PATZ

Monica Fedele, Giovanna Maria Pierantoni, Pierlorenzo Pallante, Alfredo Fusco

https://doi.org/10.4081/jnai.3988

4464

PDF: 666
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Predictive molecular markers for EGFR-TKI in non-small cell lung cancer patients: new insights and critical aspects

Paola Ulivi, Daniele Calistri, Wainer Zoli, Dino Amadori

e10

https://doi.org/10.4081/jnai.1805

1216

PDF: 577

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Survival of the fittest or best adapted: HLA-dependent tumor development

Giuseppe V. Masucci, Emilia Andersson, Lisa Villabona, Hildur Helgadottir, Kjell Bergfeldt, Federica Cavallo, Guido Forni, Soldano Ferrone, Aniruddha Choudhury, Barbara Seliger, Rolf Kiessling

e9

https://doi.org/10.4081/jnai.1654

1820

PDF: 675

HTML: 3511
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Cancer immunoediting and dioxin-activating aryl hydrocarbon receptor: a missing link in the shift toward tumor immunoescape?

Ruggero Ridolfi, Massimo Guidoboni, Laura Ridolfi

https://doi.org/10.4081/jnai.1724

1762

PDF: 599

HTML: 21058
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Induced pluripotent stem cells: the long-expected revolution in medical science and practice?

Antonio Sorrentino

https://doi.org/10.4081/jnai.1625

1235

PDF: 623

HTML: 647
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Protocols

A modified Phenol-chloroform extraction method for isolating circulating cell free DNA of tumor patients

Clemens Hufnagl, Markus Stöcher, Martin Moik, Roland Geisberger, Richard Greil

https://doi.org/10.4081/jnai.4282

10442

PDF: 2266
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Practical strategies for the evaluation of high-affinity protein/nucleic acid interactions

Sarah E. Altschuler, Karen A. Lewis, Deborah S. Wuttke

https://doi.org/10.4081/jnai.4646

4370

PDF: 1362
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