https://doi.org/10.4081/jnai.1625

Induced pluripotent stem cells: the long-expected revolution in medical science and practice?

Featured Articles
Submitted: 14 January 2010
Accepted: 4 February 2010
Published: 1 March 2010
Stem cells, Molecular Medicine, Hematology, Oncology,
Abstract Views: 1243
PDF: 626
HTML: 648
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Antonio Sorrentino
antonio.sorrentino@iss.it
Dept. Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Within the matter of a few years, development of the somatic reprogramming technology to generate induced pluripotent stem (iPS) cells has contributed enormously to the stem cell research field. We learned that differentiated adult cells possess an unrestricted plasticity that allows them to be driven back to their embryonic or pluripotent state, but owing to the juvenile nature of this novel science chapter, there are many unanswered questions and dilemmas. It is indisputable, however, that iPS cells potentially could represent the jack-of-all-trades remedy in areas of medicine ranging from toxicology screening to regenerative medicine. In this review I will summarize the current strategies employed to reprogram somatic cells and the major promises and hurdles for the future of iPS cells.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

Supporting Agencies

How to Cite

Sorrentino, A. (2010). Induced pluripotent stem cells: the long-expected revolution in medical science and practice?. Journal of Nucleic Acids Investigation. https://doi.org/10.4081/jnai.1625
Copyright (c) 2010 Antonio Sorrentino Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.