Infectious Disease Reports <p><strong>Infectious Disease Reports</strong> is an online-only, international, open access peer-reviewed journal that publishes scientific papers about infectious diseases. Manuscripts dealing with research, biology, epidemiology, clinical aspects of all infection-related diseases are welcome.&nbsp;<strong>Infectious Disease Reports</strong> publishes original articles, reviews, brief reports and case reports.</p> en-US <p><strong>PAGEPress</strong> has chosen to apply the&nbsp;<a href="" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a>&nbsp;(CC BY-NC 4.0) to all manuscripts to be published.<br><br> An Open Access Publication is one that meets the following two conditions:</p> <ol> <li>the author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.</li> <li>a complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.</li> </ol> <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.</li> </ol> (Emanuela Fusinato) (Tiziano Taccini) Tue, 26 Feb 2019 00:00:00 +0100 OJS 60 Point prevalence survey of healthcare-associated infections and antimicrobial use in Kosovo hospitals <p>Health care-associated infections (HAIs) and antimicrobial resistance constitute a major public health challenge. The aim of this study was to assess the prevalence rate of HAIs and antimicrobial use in acute care hospitals in Kosovo. A multicenter study was performed in all hospitals in Kosovo. The standardized protocol for Point Prevalence Survey (PPS) on HAIs and antimicrobial use developed by European Center for Disease Control and Prevention (ECDC) was used for this survey. A total of 915 patients were included in PPS. Countrywide prevalence rate of HAIs was 4.9%. The highest rate was noticed in tertiary care level in University Clinical Centre of Kosovo (UCCK) (7.2%). The most common type of HAI was surgical site infection, representing 35.5% of all reported HAIs. Prevalence of HAIs was highest in surgical departments (46.6%). The median length of stay before onset of HAI was 11 days (range: 3-27 days). Gram negative bacteria were the predominant microorganisms (61% of cases). From all patients, 520 (56.8%) of them were using at least one antibiotic. Ceftriaxone was the most prescribed antibiotic with 40.3%. Antibiotics were administered mainly through parenteral route (93.8%). Empiric treatment was the physician’s choice for prescribing in 87.1%. The main reason for antibiotic treatment was pneumonia (19.8%). Medical prophylaxis was reported in 10% of antibiotic prescriptions. Key recommendations driven by this study are to improve surveillance systems of HAI and antibiotic use, enhance infection prevention and control and establish antimicrobial stewardship program.</p> Lul Raka, Gazmend Spahija, Agreta Gashi-Gecaj, Astrit Hamza, Edita Haxhiu, Albiona Rashiti, Gëzim Rrahimi, Selvete Hyseni, Nicola Petrosillo ##submission.copyrightStatement## Tue, 19 Mar 2019 08:18:57 +0100 Strength training improves body composition, muscle strength and increases CD4+ T lymphocyte levels in people living with HIV/AIDS <p>The establishment of physical training programs for people living with HIV/AIDS (PLWHA) has several benefits. The study aimed to analyze the effect of resistance training using prediction of intensity by subjective perception of effort (SPE) on body composition, muscle strength, and TCD4+ lymphocyte levels in PLWHA. This a randomized controlled trial study. Participants (11 men and 8 women), were divided in two groups: exercise group (EG) and control group (CG). The EG was submitted to 12 weeks of a resistance-training program based in the prediction of intensity by SPE. Body mass percentages were evaluated using tetrapolar bioelectrical impedance and skinfold methods. We used Flow Cytometry to quantify CD4+ T lymphocytes. Patients showed significant changes in Body Fat Percentage (Δ%=-6.23%), Lean Body Mass (Δ%=2.45%), and CD4T lymphocytes levels (Δ%=15.77%). They also showed significant increase in muscular strength presented in the test for one repetition maximum in all the evaluated exercises. Our data suggest that exercising program prescribed by SPE is capable of improving immune function, body composition, and muscular strength in PLWHA.</p> José Garcia de Brito-Neto, Micássio Fernandes de Andrade, Valéria Duarte de Almeida, Dayane Carla Costa Paiva, Nickson Melo de Morais, Christiane Medeiros Bezerra, José Veríssimo Fernandes, Ellany Gurgel Cosme do Nascimento, Ivana Alice Teixeira Fonseca, Thales Allyrio Araújo de Medeiros Fernandes ##submission.copyrightStatement## Thu, 23 May 2019 09:35:14 +0200 Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa <p>Measles is a respiratory disease caused by the measles virus (MV) belonging to the <em>Paramyxovirus</em> family and the <em>Morbillivirus</em> genus. Due to a failure in maintaining immunization coverage in some countries, measles is a re-emerging disease in the human population, especially in Africa. The aim of this study was to describe a measles epidemic in Gabon. At first, a syndromic surveillance was set up. Blood samples from febrile patients with maculopapular rash were taken and sent to the measles reference center in Cameroon for laboratory confirmation. Between March and May 2016, 79 clinically suspected cases were reported including 82.3% (n=65) and 17.7% (n=14) in Oyem and Libreville, respectively. In total, 39.2% (n=31) of children were 11 months-old, 34.2% (n=27) were children aged 1 to 4 years, 11.4% (n=9) were older children from 5 to 9 years, 6.3% (n=5) of children were aged 10 to 15 years and 8.9% (n=7) were 15 years and older. 53.3% (16/30) were laboratory confirmed. This measles outbreak reiterates the importance of maintaining a high level of vaccine coverage in Gabon for vaccine-preventable diseases, as well as the usefulness of a near-real-time surveillance system for the detection of infectious diseases.</p> Pater Noster Sir-Ondo-Enguier, Edgard Brice Ngoungou, Yves-Noel Nghomo, Larson Boundenga, Priscille Moupiga-Ndong, Euloge Ibinga, Xavier Deparis, Jean-Bernard Lékana-Douki ##submission.copyrightStatement## Thu, 23 May 2019 13:27:44 +0200 Right-sided endocarditis from Staphylococcus lugdunensis in a patient with tetralogy of Fallot <p>Infective endocarditis is often caused by bacterial pathogens and can affect native and prosthetic tissue. Common pathogens in pediatric patients include <em>Staphylococcus</em> aureus, viridans group streptococci, enterococcal species and coagulase-negative staphylococci, though culture-negative cases are not uncommon. Coagulase-negative staphylococci present a conundrum to clinicians due to the potential of culture contamination. While <em>Staphylococcus lugdunensis</em> is a coagulase-negative staphylococcus, it is an emerging cardiotropic pathogen that presents similarly to <em>Staphylococcus aureus.</em> Here we report a case of a child with repaired tetralogy of Fallot found to have right-sided infective endocarditis caused by <em>Staphylococcus lugdunensis.</em></p> Bradford III Becken, Jacob Kilgore, Elizabeth Thompson, M. Anthony Moody ##submission.copyrightStatement## Tue, 26 Feb 2019 09:34:57 +0100