Klinefelter syndrome and cutaneous localization of diffuse large B cell lymphoma: a real connection or a casual association?


https://doi.org/10.4081/dr.2023.9812
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Authors

  • Federica Scarfì
    scarfif@gmail.com
    Dermatology Unit, Toscana Centro Local Health Unit, Prato Hospital; Section of Dermatology, Department of Health Sciences, University of Florence, Italy.
  • Elisabetta Magnaterra Dermatology Unit, Toscana Centro Local Health Unit, Prato Hospital; Section of Dermatology, Department of Health Sciences, University of Florence, Italy.
  • Simone Santini Hematology and Oncohematology Unit, Toscana Centro Local Health Unit, Prato Hospital, Italy.
  • Franca Taviti Dermatology Unit, Toscana Centro Local Health Unit, Prato Hospital, Italy.

Diffuse large B cell lymphoma (DLBCL) is a common aggressive subtype of non-Hodgkin lymphoma, accounting for nearly 30-40% of all cases. This condition can affect the skin both primarily and secondarily. Herein we report a clinical and dermoscopic case of skin metastasis of DLBCL in a patient with Klinefelter syndrome.