Evans’ syndrome following vaccination with ChAdOx1 nCoV-19 in a patient with new-onset localized scleroderma

Thilo Gambichler; Pia Nordmann; Christina Scheel; Laura Susok

doi:10.4081/dr.2022.9470

Growing evidence suggests that COVID-19 vaccines can induce hematological conditions. Here, we report a case of Evans’ syndrome, a combination of immune thrombocytopenic purpura and autoimmune hemolytic anemia following administration of the ChAdOx1 nCoV-19 vaccine. The present case further supports the notion that COVID-19 vaccines can trigger in rare cases severe persistent autoimmune-mediated hematological conditions which may predominantly occur in patients with underlying autoimmune conditions.

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Gambichler, T., Nordmann, P., Scheel, C., & Susok, L. (2022). Evans’ syndrome following vaccination with ChAdOx1 nCoV-19 in a patient with new-onset localized scleroderma. Dermatology Reports, 14(4). https://doi.org/10.4081/dr.2022.9470