Case of generalized morphea complicated with systemic sclerosis


Published: 6 October 2021
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Dear Editor,
Localized scleroderma (LSc; morphea) is a rare fibrosing disease of the skin and underlying tissues, which is different from systemic sclerosis (SSc). 1 LSc is classified based on clinical presentations: circumscribed, linear, generalized, pansclerotic, and mixed morphea. 1 Generalized morphea (GM) , which is characterized by widespread skin lesions with multiple indurated plaques or hyperpigmentation, is a relatively rare subtype occurring in 7-9% of patients with LSc. 1 Previous studies have shown that SSc can be complicated by GM, separately from GM-like SSc. Here, we present a rare case of coexistence of LSc and SSc in which LSc skin lesions appeared before SSc became apparent [...].


Sawamura, S., Makino, K., Nakashima, H., Makino, T., & Fukushima, S. (2021). Case of generalized morphea complicated with systemic sclerosis. Dermatology Reports. https://doi.org/10.4081/dr.2021.9382

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