https://doi.org/10.4081/hmr.v2i5.742
0
0
0
0
Smart Citations
0
0
0
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Aurora kinase inhibitor: AS703569

Authors

A Gianella-Borradori
support@pagepress.org
Aurora kinase (AK) functions are associated with centrosome maturation, mitotic spindle organization, chromosome separation and condensation as well as cytokinesis. Inappropriate expression of aurora kinases can induce centrosome irregularities and chromosomal instability, which cause aneuploidy and malignant cell transformation. Inhibition of AK leads to abnormal mitosis with slippage through the spindle checkpoint, formation of large multilobated nuclei following additional cycles of DNA replication without cytokinesis and eventually cell death.

Dimensions

Altmetric

PlumX Metrics

Downloads

Citations

Crossref
0
Scopus
0
Google Scholar
Europe PMC

Supporting Agencies

How to Cite

Gianella-Borradori, A. (2009). Aurora kinase inhibitor: AS703569. Hematology Meeting Reports (formerly Haematologica Reports), 2(5). https://doi.org/10.4081/hmr.v2i5.742
Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).