Detoxification enzyme polymorphisms as risk factors fo t-AML

Published: June 16, 2009
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Todate, therapy-related myelodysplastic syndromes/acute Myeloid Leukemias (t-MDS/ AML) represent the main long-term adverse effect of cancer treatment. The identification of new prognostic factors has raised the question whether reducing treatment intensity in good prognosis patients may save them from long term-toxicity, without impairing response rates.

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Voso, M. T., D’Alò, F., & Leone, G. (2009). Detoxification enzyme polymorphisms as risk factors fo t-AML. Hematology Meeting Reports (formerly Haematologica Reports), 2(15). https://doi.org/10.4081/hmr.v2i15.604