Cyclophosphamide in chronic lymphocytic leukemia first line: final results of Chronic Lymphocytic Leukemia 8 Study

Published: June 12, 2009
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The prognosis of patients with CLL (chronic lymphocytic leukemia) is extremely variable. The overall median survival is about 10 years, but besides patients whose disease has an indolent course and who have a survival no different from that of the general population, there are others who have a rapidly evolving and fatal course.1 Clinical staging (Rai et al. 1975 and Binet et al. 1981) at diagnosis remains the gold standard system for deciding when to treat a patient with CLL.2

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Gobbi, M. (2009). Cyclophosphamide in chronic lymphocytic leukemia first line: final results of Chronic Lymphocytic Leukemia 8 Study. Hematology Meeting Reports (formerly Haematologica Reports), 3(3). https://doi.org/10.4081/hmr.v3i3.581