The impact of diagnosis on the therapeutic management of chronic lymphocytic leukemia

Published: June 12, 2009
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The considerable progress in diagnostic tools, the identification of a number of biological markers improving outcome prediction, and the introduction of new treatment strategies have made the therapeutic management of chronic lymphocytic leukemia (CLL) no longer straightforward. Furthermore, the care of individual patients with CLL has become more demanding, and a comprehensive approach to them should include attention to quality of life (QOL) issues, adherence to supportive care guidelines, consideration of age and comorbidity, recognition of clinical complications such as infection, autoimmune cytopenias, and transformation into a more aggressive disease.1 In CLL patients, a risk-stratified approach to therapy based on novel prognostic markers is recommended in the context of clinical trials, but not in general routine. 2 How the novel markers could at least complement the traditional prognostic factors in the clinical management of patients with CLL is now discussed.3

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Liso, V., & Rizzi, R. (2009). The impact of diagnosis on the therapeutic management of chronic lymphocytic leukemia. Hematology Meeting Reports (formerly Haematologica Reports), 3(3). https://doi.org/10.4081/hmr.v3i3.579