What is gene profiling contributing to the characterization of chronic lymphocytic leukemia

Published: June 12, 2009
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Gene profiling is a technology that allows to assess simultaneously the levels of expression of thousands of genes in a given cell sample using a single chip. This revolutionary technology has witnessed important applications in the study of acute and chronic hematologic malignancies. These can impact on the diagnostic work-up, on the prognostic stratification, on the correlation with the response to treatment and on the design of innovative therapeutic strategies, as well as on a better understanding of the biologic properties of the leukemic cells and of the non-neoplastic accessory cell populations. This innovative technology has been successfully applied to the study of CLL.

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Foà, R., Guarini, A., Del Giudice, I., Tavolaro, S., & Chiaretti, S. (2009). What is gene profiling contributing to the characterization of chronic lymphocytic leukemia. Hematology Meeting Reports (formerly Haematologica Reports), 3(3). https://doi.org/10.4081/hmr.v3i3.578