Treatment of natural killer/T-cell lymphoma

Published: June 11, 2009
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NK (natural killer) neoplasm is rare and extranodal NK/T-cell lymphoma, nasal type, is the commonest NK cell neoplasm. Historically, different names have been used to describe this extraordinary nasal lesion. It has been called lethal midline granuloma, midline malignant reticulosis and polymorphic reticulosis.1-4 The lesion was not specifically categorized in the previous lymphoma classification systems: Rappaport, Kiel or Working Formulation. In the REAL Classification, it has been called angiocentric lymphoma but angiocentricity is by no means pathognomonic of NK neoplasms.5 In the Revised WHO classification, two NK neoplasms are described: extra-nodal NK/Tcell lymphoma, nasal type and aggressive NK cell leukaemia.6,7

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Liang, R. (2009). Treatment of natural killer/T-cell lymphoma. Hematology Meeting Reports (formerly Haematologica Reports), 3(1). https://doi.org/10.4081/hmr.v3i1.523