First line therapy for peripheral T-cell lymphoma

Published: June 11, 2009
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T-cell non-Hodgkin's lymphomas (NHL) are rare in Europe and the United States, where they constitute about 10-15% of aggressive lymphomas. The prognostic significance of the immunophenotype has been explored in several studies and results have been reported concerning the outcome of PTCL compared to that of B-cell lymphomas (BCL). PTCL patients were found to have generally poorer prognoses than patients with BCL. However, PTCL represent a heterogeneous group of lymphomas and a wide variety of different histological subtypes have been recognized. The most common subtype is an heterogeneous group of PTCL not other specified (PTCL-NOS), followed by anaplastic large cell lymphoma (ALCL), angioimmunoblastic Tcell lymphoma (AITL). Some uncommon PTCL subtypes have been included in series and are not always easy to identify in reports.

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Sibon, D. (2009). First line therapy for peripheral T-cell lymphoma. Hematology Meeting Reports (formerly Haematologica Reports), 3(1). https://doi.org/10.4081/hmr.v3i1.522