https://doi.org/10.4081/hmr.v2i10.446

Diagnostic criteria of hypogammaglobulinemia in infancy

Vol. 2 No. 10: Vth International Neonatal Hematology and Immunology Meeting
Published: June 9, 2009
Abstract Views: 184
PDF: 365
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Authors

V Lougaris
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A Soresina
A Meini
E Vettore
G Cattaneo
A Plebani
Of all of the primary immunodeficiency diseases, those affecting B cell function are the most frequent. Selective absence of serum and secretory IgA is the most common defect, with rates ranging from 1/333 persons to 1/16.000 among different race. By contrast, it has been estimated that hypo/agammaglobulinemia occurs with a frequency of only 1/50.000 persons. Patients with antibody deficiency are usually recognized because they have recurrent infections with encapsulated bacteria or a history of failure to respond to antibiotic treatment, but some individuals, mainly those affected by IgA deficiency or transient hypogammaglobulinemia of infancy, may have few or no infections.

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Lougaris, V., Soresina, A., Meini, A., Vettore, E., Cattaneo, G., & Plebani, A. (2009). Diagnostic criteria of hypogammaglobulinemia in infancy. Hematology Meeting Reports (formerly Haematologica Reports), 2(10). https://doi.org/10.4081/hmr.v2i10.446
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