https://doi.org/10.4081/hmr.v2i7.428

Allogeneic transplantation for multiple myeloma

Vol. 2 No. 7: New Insights in Hematology, Venice (Italy), May 14-17, 2006
Published: June 8, 2009
Abstract Views: 184
PDF: 188
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

I Majolino
support@pagepress.org
E Carnevall
A Locasciulli
P Di Bartolomeo
R Scimè
P Corradini
C Selleri
F Selleri
In multiple myeloma (MM), the standard of treatment for patients < 65 years is high-dose chemotherapy followed by autologous stem cell transplantation. However, following either a single or a tandem autograft MM invariably recurs due to the persistence of tumor cells either in the host and/or in the graft. Purification procedures have generally proved unsuccessful. Allogeneic transplantation not only skips graft tumor contamination, but also exerts an immune effect against the myeloma clone. This effect is also displayed by donor lymphocytes when infused to the recipient in adeguate amounts. Despite these biological advantages, the precinse role of allograft in MM remains controversial.

Dimensions

Altmetric

PlumX Metrics

Downloads

Citations

Crossref
Scopus
Google Scholar
Europe PMC

Supporting Agencies

How to Cite

Majolino, I., Carnevall, E., Locasciulli, A., Di Bartolomeo, P., Scimè, R., Corradini, P., Selleri, C., & Selleri, F. (2009). Allogeneic transplantation for multiple myeloma. Hematology Meeting Reports (formerly Haematologica Reports), 2(7). https://doi.org/10.4081/hmr.v2i7.428
Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).