https://doi.org/10.4081/hmr.v2i3.373

Non steroidal anti-inflammatory drugs and COX-2 inhibitors as anti-angiogenic drugs

Vol. 2 No. 3: Cervo Preclinical Working Conference, Cervo Ligure, October 6-8, 2005
Published: June 8, 2009
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C Rüegg
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Non-steroidal anti-inflammatory drugs (NSAIDs) and specific inhibitors of cyclooxygenase (COX)-2, collectively referred to as COX-2 inhibitors, are therapeutics widely used for the treatment of pain, inflammation and fever. Experimental and clinical evidence indicate that COX-2 is a potential therapeutic target in cancer, and that NSAIDs and COX-2 inhibitors (COXIBs) also have anti-cancer activity.1,2 COX-2 is expressed by cancer cells and cells of the tumor stroma during tumor progression and in response to chemotherapy or radiotherapy.

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Rüegg, C. (2009). Non steroidal anti-inflammatory drugs and COX-2 inhibitors as anti-angiogenic drugs. Hematology Meeting Reports (formerly Haematologica Reports), 2(3). https://doi.org/10.4081/hmr.v2i3.373
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