https://doi.org/10.4081/hmr.v2i3.372

Regulation of integrin function controls angiogenic remodeling

Vol. 2 No. 3: Cervo Preclinical Working Conference, Cervo Ligure, October 6-8, 2005
Published: June 8, 2009
Abstract Views: 133
PDF: 274
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Authors

G Serini
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F Bussolino
ertebrates evolved a cardiovascular system capable of transporting over long distances oxygen and nutrients to the many different tissues that compose their multicellular organism. Two distinct morphogenetic processes contribute to the development of the embryonic vasculature: vasculogenesis and angiogenesis.1 During vasculogenesis, mesodermal cells differentiate into endothelial cell (EC) precursors (angioblasts), which proliferate and coalesce into a primitive network of homogeneously sized vessels known as primary capillary plexus.

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Serini, G., & Bussolino, F. (2009). Regulation of integrin function controls angiogenic remodeling. Hematology Meeting Reports (formerly Haematologica Reports), 2(3). https://doi.org/10.4081/hmr.v2i3.372
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