Zoledronic acid impairs mammary carcinogenesis in BALB/c mice transgenic for the Her-2/neu oncogene

Published: June 8, 2009
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Zoledronic acids (Zol) is the most potent aminobisphosphonate clinically available.1 Preclinical in vivo data suggest that it modulates the development of bone disease, decreases tumor burden2 with a direct anti-cancer activity,3-5 and reduces the migration and the metastatic invasion of cancer cells.6

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Coscia, M., Quaglino, E., Curcio, C., Pantaleoni, F., Forni, G., & Massaia, M. (2009). Zoledronic acid impairs mammary carcinogenesis in BALB/c mice transgenic for the Her-2/neu oncogene. Hematology Meeting Reports (formerly Haematologica Reports), 2(3). https://doi.org/10.4081/hmr.v2i3.370