Reciprocal activating interaction between dendritic cells and aminobiphosphonates-stimulated T cells: role of CD86 and inflammatory cytokines

Published: June 8, 2009
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ognate interactions are a common feature of the acquired immune response, where intimate cell contacts govern critical events such as Ag presentation and delivery of T cell help to CTLs and B cells, while the coordinated control of innate immunity is mostly mediated by cytokine loops. However, a number of studies recently highlighted the importance of DC interactions with NK cells, an important effector cell type of innate immunity, in the regulation of DC maturation.1,2,3

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Conti, D., Casetti, R., Cardone, M., Varano, B., Martino, A., Belardelli, F., Poccia, F., & Gessani, S. (2009). Reciprocal activating interaction between dendritic cells and aminobiphosphonates-stimulated T cells: role of CD86 and inflammatory cytokines. Hematology Meeting Reports (formerly Haematologica Reports), 2(3). https://doi.org/10.4081/hmr.v2i3.361