https://doi.org/10.4081/hmr.v2i3.356

Alkylamines and bisphosphonates: a common mechanism for activation of

Vol. 2 No. 3: Cervo Preclinical Working Conference, Cervo Ligure, October 6-8, 2005
Published: June 5, 2009
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PDF: 361
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K Thompson
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MJ Rogers
The major subset of gd T-cells in humans (Vg9Vd2+) are activated by three distinct classes of stimulatory molecules: pyrophosphomonoesters, such as isopentenyl diphosphate (IPP) and bromohydrin diphosphate (BrHPP); nitrogen-containing bisphosphonates (N-BPs), such as alendronate (ALN), pamidronate (PAM) and zoledronic acid (ZOL); and alkylamines, such as sec-butylamine (SBA) and iso-butylamine (IBA).

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Thompson, K., & Rogers, M. (2009). Alkylamines and bisphosphonates: a common mechanism for activation of. Hematology Meeting Reports (formerly Haematologica Reports), 2(3). https://doi.org/10.4081/hmr.v2i3.356
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