Hemorrhage and thrombosis in acute leukemia

Published: June 3, 2009
Abstract Views: 367
PDF: 3578
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Patients with acute leukaemias are at high risk of both hemorrhage and thrombosis. This risk is different according to: 1. the type of leukemia, i.e.: acute myeloblastic leukemia (AML), acute lymphoblastic leukemia (ALL), or acute promyelocytic leukemia (APL); and 2. the phase of treatment, i.e.: onset of the disease, remission induction, consolidation. Among bleeding complications, of particular importance is the disseminated intravascular coagulation (DIC) syndrome, due to the massive intravascular activation of blood coagulation with consumption of clotting factors and platelets, leading to severe haemorrhages. Thrombosis of large vessels is a more rare complication, although recent data indicate that it can be a relevant problem at the onset of AML, and during induction chemotherapy in ALL.

Dimensions

Altmetric

PlumX Metrics

Downloads

Citations

Supporting Agencies

How to Cite

Barbui, T. (2009). Hemorrhage and thrombosis in acute leukemia. Hematology Meeting Reports (formerly Haematologica Reports), 1(9). https://doi.org/10.4081/hmr.v1i9.327