https://doi.org/10.4081/hmr.v1i9.321

Vitamin k, warfarin and prothrombin: an alternate pathway to improve cancer survival

Vol. 1 No. 9: 3rd International Conference on Thrombosis and Hemostasis Issues in Cancer, Bergamo, October 14-16, 2005
Published: June 3, 2009
Abstract Views: 167
PDF: 233
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

HA Liebman
support@pagepress.org
Billroth first proposed a theoretical relationship between hemostatic mechanisms and the development of cancer metastasis in 1878. A lack of experimental animal models to study cancer metastasis inhibited further studies on hemostasis and cancer until the late 1960s and early 1970s.1 Since that time, studies using mouse and rat models, have demonstrated a reduction of tumor metastasis and improved animal survival with systemic anticoagulation. However, the therapeutic benefits observed in these models cannot be attributed to a single, specific intervention in the coagulation system since a variety of anticoagulants, anti-platelet and fibrinolytic agents appeared to be effective.1

Dimensions

Altmetric

PlumX Metrics

Downloads

Citations

Crossref
Scopus
Google Scholar
Europe PMC

Supporting Agencies

How to Cite

Liebman, H. (2009). Vitamin k, warfarin and prothrombin: an alternate pathway to improve cancer survival. Hematology Meeting Reports (formerly Haematologica Reports), 1(9). https://doi.org/10.4081/hmr.v1i9.321
Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).