Oral fludarabine

Published: June 3, 2009
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Fludarabine is an antimetabolite cytotoxic agent uses for the treatment of patients with various lymphoid malignancies, especially B-cell chronic lymphocytic leukemia (CLL).1 The intravenous formulation of fludarabine has been available for a number of years. It is well established as an effective first-line treatment option in CLL and preferred second-line therapy for patients with CLL initially treated with an alkylating agent-based regimen.2-4 Intravenous fludarabine had been administered as an infusion for 5 consecutive days each month for about 6 months. This schedule creates a number of difficulties with respect to convenience with repeated venipunctures and frequent outpatient visits or hospital admissions.

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How to Cite

Verhoef, G. (2009). Oral fludarabine. Hematology Meeting Reports (formerly Haematologica Reports), 1(8). https://doi.org/10.4081/hmr.v1i8.301