https://doi.org/10.4081/hmr.v1i6.267

Introduction

Vol. 1 No. 6: Von Willebrand Factor and von Willebrand disease: the state of the art in 2005
Published: May 29, 2009
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Authors

F. Rodeghiero
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P.M. Mannucci
When Eric von Willebrand, almost 80 years ago, first described a family with a new hemorrhagic disease, he could hardly imagine that his seminal discover was opening new frontiers of research in a fascinating area of investigation, still very active and fruitful at the beginning of the third millennium. Moving from the recognition, in early ’70, that the intriguing bleeding disorder called after his name (von Willebrand disease, VWD) is caused by quantitative or qualitative defects of the plasma protein von Willebrand factor (VWF), we are now understanding more and more its molecular structure, functional domains, multimeric assembly and pleiotropic functions.

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How to Cite

Rodeghiero, F., & Mannucci, P. (2009). Introduction. Hematology Meeting Reports (formerly Haematologica Reports), 1(6). https://doi.org/10.4081/hmr.v1i6.267
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