https://doi.org/10.4081/hmr.v1i5.263

Pathology of Helicobacter pylori-associated lymphomas

Vol. 1 No. 5: International Symposium on Infection-Driven Lymphomas, Rome, April 17-19, 2005
Published: May 29, 2009
Abstract Views: 225
PDF: 103
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Axel Greiner
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The stomach is the commonest site of MALT-type lymphoma development, although the gastric mucosa is primarily devoid of lymphoid tissue. Helicobacter pylori leads to an active chronic gastritis and to the recruitment to of both B cells and T cells to mucosa forming mucosa-associated lymphoid tissue (MALT). In the recent decade evidence accumulated that Helicobacter pylori infection is linked to the pathogenesis of gastric MALT-type lymphoma. Antigen- with T-cell stimulation may have important impact on the initial phase of tumor development, while Helicobacter pylori eradication can result in tumor regression in most cases.

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Greiner, A. (2009). Pathology of Helicobacter pylori-associated lymphomas. Hematology Meeting Reports (formerly Haematologica Reports), 1(5). https://doi.org/10.4081/hmr.v1i5.263
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