https://doi.org/10.4081/hmr.v1i5.259

Kshv/hhv8-associated lymphomas

Vol. 1 No. 5: International Symposium on Infection-Driven Lymphomas, Rome, April 17-19, 2005
Published: May 29, 2009
Abstract Views: 165
PDF: 238
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Antonino Carbone
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It was only after the discovery of KSHV/HHV8, that primary effusion lymphoma (PEL) could be recognized as a distinct entity, thanks to its consistent association with HHV-8 infection. As a consequence, PEL has been included in the recent WHO lymphoma classification, within the group of lymphomas occurring more specifically in HIV positive patients. PEL is a rare subset of AIDS non-Hodgkin’s lymphoma predominantly growing in the pleural, pericardial, and peritoneal cavities as neoplastic effusions, usually without a contiguous tumor mass. Morphologically, PEL shows features bridging immunoblastic and anaplastic large-cell lymphomas, and frequently displays a certain degree of plasma cell differentiation.

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Carbone, A. (2009). Kshv/hhv8-associated lymphomas. Hematology Meeting Reports (formerly Haematologica Reports), 1(5). https://doi.org/10.4081/hmr.v1i5.259
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