Anisakis simplex and urticaria. What we know about its real incidence and management in dermatological settings?
https://doi.org/10.4081/dr.2023.9819
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Acute or chronic infections have been described among causes of chronic urticaria (CU). Anisakidosis is a human disease caused by the ingestion of larval nematodes of the family Anisakidae. The infestation is acquired by eating raw seafood or undercooked fish and squid. There are considerable variations in the frequency of underlying causes in the different studies and in different countries, such as differences in diets and the prevalence of infections. Anisakis simplex has been recognized as a trigger of both acute and CU manifestations. However, there is still a lack of evidence about its management and treatment in dermatology. We, therefore, reviewed some biologic properties of Anisakis simplex in order to understand the relationship between its biology and the mechanism it uses to establish chronic dermatological conditions such as urticaria and cause late complications. In addition, we herein report some concerns about the effectiveness of systemic treatment in preventing complications and management in dermatological settings.
Viñas M, Postigo I, Suñén E, Martínez J (2020) Urticaria and silent parasitism by Ascaridoidea: Component-resolved diagnosis reinforces the significance of this association. PLoS Negl Trop Dis 14(4):e0008177. DOI: https://doi.org/10.1371/journal.pntd.0008177
Zuberbier T, Abdul Latiff AH, Abuzakouk M, Aquilina S, Asero R, Baker D, Ballmer-Weber B, Bangert C, Ben-Shoshan M, Bernstein JA, Bindslev-Jensen C, Brockow K, Brzoza Z, Chong Neto HJ, Church MK, Criado PR, Danilycheva IV, Dressler C, Ensina LF, Fonacier L, Gaskins M, Gáspár K, Gelincik A, Giménez-Arnau A, Godse K, Gonçalo M, Grattan C, Grosber M, Hamelmann E, Hébert J, Hide M, Kaplan A, Kapp A, Kessel A, Kocatürk E, Kulthanan K, Larenas-Linnemann D, Lauerma A, Leslie TA, Magerl M, Makris M, Meshkova RY, Metz M, Micallef D, Mortz CG, Nast A, Oude-Elberink H, Pawankar R, Pigatto PD, Ratti Sisa H, Rojo Gutiérrez MI, Saini SS, Schmid-Grendelmeier P, Sekerel BE, Siebenhaar F, Siiskonen H, Soria A, Staubach-Renz P, Stingeni L, Sussman G, Szegedi A, Thomsen SF, Vadasz Z, Vestergaard C, Wedi B, Zhao Z, Maurer M (2022) The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy 77(3):734-766. DOI: https://doi.org/10.1111/all.15090
Montoro A, Perteguer MJ, Chivato T, Laguna R, Cuéllar C (1997) Recidivous acute urticaria caused by Anisakis simplex. Allergy 52(10): 985-991. DOI: https://doi.org/10.1111/j.1398-9995.1997.tb02418.x
Rama TA, Silva D (2021) Anisakis Allergy: Raising Awareness. Acta Med Port doi: 10.20344/amp.15908. DOI: https://doi.org/10.20344/amp.15908
Cavallero S, Martini A, Migliara G, De Vito C, Iavicoli S, D'Amelio S (2018) Anisakiasis in Italy: Analysis of hospital discharge records in the years 2005-2015. PLoS One 13(12): e0208772. doi: 10.1371/journal.pone.0208772. DOI: https://doi.org/10.1371/journal.pone.0208772
AAITO-IFIACI Anisakis Consortium (2011) Anisakis hypersensitivity in Italy: prevalence and clinical features: a multicenter study. Allergy 66(12):1563-1569. DOI: https://doi.org/10.1111/j.1398-9995.2011.02691.x
Kojima G, Usuki S, Mizokami K, Tanabe M, Machi J (2013) Intestinal anisakiasis as a rare cause of small bowel obstruction. Am J Emerg Med 31(9): 1422.e1-2. DOI: https://doi.org/10.1016/j.ajem.2013.05.015
Mazzucco W, Raia DD, Marotta C, Costa A, Ferrantelli V, Vitale F, Casuccio A (2018) Anisakis sensitization in different population groups and public health impact: A systematic review. PLoS One 13(9):e0203671. DOI: https://doi.org/10.1371/journal.pone.0203671
Sudduth RH. Anisakidosis. Strickland: Hunter’s tropical medicine and emerging infectious diseases. 8th ed. Philadelphia: WB Saunders, 2000.
Van Thiel PH (1960)A nematode parasitic to herring, causing acute abdominal syndromes in man. Trop Geogr Med 2:97–113.
Caraballo L, Coronado S (2018) Parasite allergens. Mol Immunol 100:113-119. DOI: https://doi.org/10.1016/j.molimm.2018.03.014
Daschner A, Alonso-Gómez A, Cabañas R, Suarez-de-Parga JM, López-Serrano M (2000) Gastroallergic anisakiasis: Borderline between food allergy and parasitic disease—Clinical and allergologic evaluation of 20 patients with confirmed acute parasitism by Anisakis simplex. J Allergy Clin Immunol 105(1 Pt 1):176-181. doi: 10.1016/s0091-6749(00)90194-5. DOI: https://doi.org/10.1016/S0091-6749(00)90194-5
Daschner A, De Frutos C, Valls A, Vega F (2010) Anisakis simplex sensitization-associated urticaria: short-lived immediate type or prolonged acute urticaria. Arch Dermatol Res 302(8): 625-629. DOI: https://doi.org/10.1007/s00403-010-1069-9
Cuéllar C, Daschner A, Valls A, De Frutos C, Fernández-Fígares V, Anadón AM, Rodríguez E, Gárate T, Rodero M, Ubeira FM (2012) Ani s 1 and Ani s 7 recombinant allergens are able to differentiate distinct Anisakis simplex-associated allergic clinical disorders. Arch Dermatol Res 304(4):283-288. DOI: https://doi.org/10.1007/s00403-012-1206-8
Sudharson S, Kalic T, Hafner C, Breiteneder H (2021). Newly defined allergens in the WHO/IUIS Allergen Nomenclature Database during 01/2019-03/2021. Allergy 76(11):3359-3373. doi: 10.1111/all.15021. DOI: https://doi.org/10.1111/all.15021
Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ (2008) Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine 26(19):2408-2417. doi: 10.1016/j.vaccine.2008.02.049. DOI: https://doi.org/10.1016/j.vaccine.2008.02.049
Farnell EJ, Tyagi N, Ryan S, Chalmers IW, Pinot de Moira A, Jones FM, Wawrzyniak J, Fitzsimmons CM, Tukahebwa EM, Furnham N, Maizels RM, Dunne DW (2015) Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection. Front Immunol 6:26. doi: 10.3389/fimmu.2015.00026. DOI: https://doi.org/10.3389/fimmu.2015.00026
Fitzsimmons CM, Stewart TJ, Hoffmann KF, Grogan JL, Yazdanbakhsh M, Dunne DW (2004) Human IgE response to the Schistosoma haematobium 22.6 kDa antigen. Parasite Immunol 26(8-9):371-376. doi: 10.1111/j.0141-9838.2004.00721.x. PMID: 15679635. DOI: https://doi.org/10.1111/j.0141-9838.2004.00721.x
Fitzsimmons CM, Jones FM, Stearn A, Chalmers IW, Hoffmann KF, Wawrzyniak J, Wilson S, Kabatereine NB, Dunne DW (2012) The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses. PLoS Negl Trop Dis 6(4):e1593. doi: 10.1371/journal.pntd.0001593. DOI: https://doi.org/10.1371/journal.pntd.0001593
Kobayashi, Y., Ishizaki, S., Shimakura, K, Nagashima Y, Shiomi K (2007) Molecular cloning and expression of two new allergens from Anisakis simplex. Parasitol Res 100, 1233–1241. https://doi.org/10.1007/s00436-006-0396-4 DOI: https://doi.org/10.1007/s00436-006-0396-4
Kobayashi Y, Ishizaki S, Nagashima Y, Shiomi K. (2008) Ani s 1, the major allergen of Anisakis simplex: purification by affinity chromatography and functional expression in Escherichia coli. Parasitol Int 57(3):314-319. doi: 10.1016/j.parint.2008.01.005. DOI: https://doi.org/10.1016/j.parint.2008.01.005
González-Fernández J, Rivas L, Luque-Ortega JR, Núñez-Ramírez R, Campioli P, Gárate T, Perteguer MJ, Daschner A, Cuéllar C (2017) Recombinant vs native Anisakis haemoglobin (Ani s 13): Its appraisal as a new gold standard for the diagnosis of allergy. Exp Parasitol 181:119-129. DOI: https://doi.org/10.1016/j.exppara.2017.08.010
Hochberg NS, Hamer DH (2010) Anisakidosis: Perils of the deep. Clin Infect Dis 51(7):806-812. doi: 10.1086/656238. PMID: 20804423. DOI: https://doi.org/10.1086/656238
European Parliament. Regulation number 853/2004 of the European Parliament and of the council of 29 April 2004. Strasbourgh: EP; 2004.
Centers for Disease Control and Prevention (CDC). Parasites - Anisakiasis. Available at: https://www.cdc.gov/parasites/anisakiasis/health_professionals/. Accessed April 9, 2022.
ML, Umpierrez A, Perez-Piñar T, Moneo I, de Burgos C, Asturias JA, Rodríguez-Pérez R (2012) Anisakis simplex recombinant allergens increase diagnosis specificity preserving high sensitivity. Int Arch Allergy Immunol 158(3):232-240. DOI: https://doi.org/10.1159/000331581
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