Clinical, dermoscopic, and histopathologic findings of hidroacanthoma simplex: a case report and literature review
https://doi.org/10.4081/dr.2022.9571
Accepted: 30 September 2022
HTML: 78
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Hidroacanthoma simplex (HS) is a rare benign intraepidermal tumor that originates in the acrosyringial portion of the eccrine duct. Clinically, they are well-defined lesions, flat or verrucous brownish plaque, and can be misdiagnosed with other types of benign or malignant tumors. Dermoscopy reveals small black globules and fine scales. The histopathology of HS is characterized by typical intraepidermal nests, well-circumscribed, composed of uniform basaloid and poroid cells within the acanthotic epidermis with cystic or ductal structures in the nests. We report a case of HS that changes its clinical appearance, dermoscopy, and histopathologic findings over time. Differential diagnoses included seborrheic keratosis, Bowen disease, melanoma, and malignant HS.
Bouhamed M, Bacha D, Abdelmoula F, et al. Clonal seborrheic keratosis: a rare skin tumor. Pan Afr Med J 2019;34:54.
Liu HN, Chang YT, Chen CC. Differentiation of hidroacanthoma simplex from clonal seborrheic keratosis - an immunohistochemical study. Am J Dermatopathol 2004;26:188-93.
Niiyama S, Oharaseki T, Mukai H. Giant hidroacanthoma simplex mimicking bowen's disease. Case Rep Dermatol 2015;7:241-4.
Furlan KC, Kakizaki P, Chartuni JCN, et al. Hidroacanthoma simplex: dermoscopy and cryosurgery treatment. An Bras Dermatol 2017;92:253-5.
Shiiya C, Hata H, Inamura Y, et al. Dermoscopic features of hidroacanthoma simplex: usefulness in distinguishing it from Bowen's disease and seborrheic keratosis. J Dermatol 2015;42:1002-5.
Souza BCE, Luce MCA, Cunha TDAC, Valente NYS. Dermatoscopy of the borst-jadassohn phenomenon in hidroacanthoma simplex. An Bras Dermatol 2020;95:95-7.
Sun Kim M, Rae Lee H, Lee JH, et al. Malignant hidroacanthoma simplex: arising in hidroacanthoma simplex mimicking clonal seborrheic keratosis. Int J Dermatol 2013;52:258-60.
Takayama R, Ansai S, Ishiwata T, et al. Expression of lumican in hidroacanthoma simplex and clonal-type seborrheic keratosis
as a potent differential diagnostic marker. Am J Dermatopathol 2014;36:655-60.
Sato Y, Fujimura T, Tamabuchi E, Haga T, Aiba S. Dermoscopy findings of hidroacanthoma simplex. Case Rep Dermatol 2014;6:154-8.
Copyright (c) 2022 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Downloads
Citations
