Late-onset focal dermal elastosis: report of a case and review of the literature
HTML: 180
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Late-onset focal dermal elastosis is a rare cutaneous condition classified as an increased dermal elastic tissue disorder. It is distinguished clinically by multiple papules with a preference for the neck and other flexures, as well as histologically by focally increased elastic fibers in the reticular dermis. Several elastic tissue disorders in the skin have a similar clinical presentation. The distinction between late-onset focal dermal elastosis and other pseudoxanthoma elasticum mimickers is critical because they are not associated with systemic lesions. We present a case of late-onset focal dermal elastosis and conduct a literature review on this unusual condition.
Tajima S, Shimizu K, Izumi T, et al. Late-onset focal dermal elastosis: clinical and histological features. Br J Dermatol 1995;133:303-5. DOI: https://doi.org/10.1111/j.1365-2133.1995.tb02634.x
Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L. Acquired disorders of elastic tissue: part I. Increased elastic tissue and solar elastotic syndromes. J Am Acad Dermatol 2004;51:1-21. DOI: https://doi.org/10.1016/j.jaad.2004.03.013
Chassaing N, Martin L, Calvas P, et al. Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations. J Med Genet 2005;42:881-92. DOI: https://doi.org/10.1136/jmg.2004.030171
Rongioletti F, Rebora A. Fibroelastolytic patterns of intrinsic skin aging: pseudoxanthoma-elasticum-like papillary dermal elastolysis and white fibrous papulosis of the neck. Dermatology 1995;191:19-24. DOI: https://doi.org/10.1159/000246478
Wang AR, Lewis K, Lewis M, Robinson-Bostom L. Papillary dermal elastosis: a unique elastic tissue disorder or an unusual manifestation of pseudoxanthoma elasticum-like papillary dermal elastolysis? J Cutan Pathol 2009;36:1010-3. DOI: https://doi.org/10.1111/j.1600-0560.2008.01183.x
Tajima S, Inazumi T, Kobayashi T. A case of acrogeria associated with late-onset focal dermal elastosis. Dermatology 1996;192:264-8. DOI: https://doi.org/10.1159/000246381
Camacho D, Machan S, Pielasinski U, et al. Familial acral localized late-onset focal dermal elastosis. Am J Dermatopathol 2012;34:310-4. DOI: https://doi.org/10.1097/DAD.0b013e31823adf2e
Wang AR, Fonder MA, Telang GH, et al. Late-onset focal dermal elastosis: an uncommon mimicker of pseudoxanthoma elasticum. J Cutan Pathol 2012;39:957-61. DOI: https://doi.org/10.1111/j.1600-0560.2012.01979.x
Knapp M, Carpenter CE, Shea K, et al. Focal Dermal Elastosis: A Proposed Update to the Nomenclature. Am J Dermatopathol 2020;42:774-5. DOI: https://doi.org/10.1097/DAD.0000000000001683
Tajima S, Tanaka N, Ohnishi Y et al. Analysis of elastin metabolism in patients with late-onset focal dermal elastosis. Acta Derm Venereol 1999;79:285-7. DOI: https://doi.org/10.1080/000155599750010670
Hanami Y, Nakamura T, Yamamoto T. Case of late-onset focal dermal elastosis. J Dermatol 2018;45:e339-e40. DOI: https://doi.org/10.1111/1346-8138.14472
Limas C. Late onset focal dermal elastosis: a distinct clinicopathologic entity? Am J Dermatopathol 1999;21:381-3. DOI: https://doi.org/10.1097/00000372-199908000-00013
Kossard S. Pseudoxanthoma-like late-onset focal dermal elastosis. Australas J Dermatol 2005;46:47-50. DOI: https://doi.org/10.1111/j.1440-0960.2004.00141.x
Higgins HJ, Whitworth MW. Late-onset focal dermal elastosis: a case report and review of the literature. Cutis 2010;85:195-7.
Tian S, Chen Z. Late-onset focal dermal elastosis. Eur J Dermatol 2012;22:399-400. DOI: https://doi.org/10.1684/ejd.2012.1664
Jansen MHE, Lijnen RLP, Lohman BGPM. Pseudoxanthoma elasticum en late onset focal dermal elastosis. Nederlands Tijdschrift voor Dermatologie en Venereologie 2014;24:652-5.
Chappell J , Kozel J , Yadira Hurley M , Vidal . A Yellow Papular Eruption on the Arms, Legs, and Neck: A Rare Masquerader. Skinmed 2016;14:465-6.
Newburger J, Foley M. Late-Onset Focal Dermal Elastosis: A Case Report and Review of the literature. Journal of the American Osteopathic College of Dermatology, Volume 41, November 2018.
Chan A, Kenet B, Shulman K, Jacobson M. Late-Onset Focal Dermal Elastosis Mimicking Pseudoxanthoma Elasticum. Am J Dermatopathol 2018;40:6.
Copyright (c) 2022 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.