Successful treatment of neuro-Behçet’s disease with infliximab: four years follow-up


https://doi.org/10.4081/rr.2015.6115
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Authors

  • Manjinder Kaur
    manjinder.kaur@tu.edu
    Department of Internal Medicine, University of Arizona College of Medicine, Tucson, AZ, United States.
  • Emily S. Nia Department of Radiology, University of Arizona College of Medicine, Tucson, AZ, United States.
  • Rebecca A. Millius Department of Pathology, University of Arizona College of Medicine, Tucson, AZ, United States.
  • Dominick G. Sudano Department of Rheumatology, University of Arizona College of Medicine, Tucson, AZ, United States.
  • Jeffrey R. Lisse Department of Rheumatology, University of Arizona College of Medicine, Tucson, AZ, United States.
Neuro-Behçet’s disease (NBD) is a rare but severe manifestation of Behçet’s disease. Patients with NBD tend to have high morbidity and mortality. Some patients do not respond adequately to conventional therapy (corticosteroids and immunosuppressants). This has led to treatment gaps in the therapy of NBD. There are reports in the literature of patients with Behçet’s disease responding to anti-TNF therapy. We present a case of a male patient with biopsy proven cerebral vasculitis presenting as NBD who has been in remission with near resolution of cerebral magnetic resonance imaging lesions for 4 years following treatment with infliximab and azathioprine.